TREATMENT OF ABNORMAL SERUM PHOSPHATE LEVELS Part of “CHAPTER 67 – DISEASES OF ABNORMAL PHOSPHATE METABOLISM“ Treatment of the myriad of diseases that characteristically display hyperphosphatemia or hypophosphatemia depends on…
CLINICAL SIGNS AND SYMPTOMS OF ABNORMAL SERUM PHOSPHATE LEVELS Part of “CHAPTER 67 – DISEASES OF ABNORMAL PHOSPHATE METABOLISM“ A wide variety of diseases and syndromes with varying clinical manifestations…
DIFFERENTIAL DIAGNOSIS OF AN ABNORMAL SERUM PHOSPHORUS LEVEL Part of “CHAPTER 67 – DISEASES OF ABNORMAL PHOSPHATE METABOLISM“ Frequently, a careful history and physical examination reveal the apparent cause of…
REGULATION OF PHOSPHATE METABOLISM Part of “CHAPTER 67 – DISEASES OF ABNORMAL PHOSPHATE METABOLISM“ The critical role that phosphorus plays in cell physiology has resulted in the development of elaborate…
DISEASES OF ABNORMAL PHOSPHATE METABOLISM Marc K. Drezner Phosphorus is one of the most abundant constituents of all tissues, and disturbances in phosphate homeostasis can affect almost any organ system….
ISCHEMIC NECROSIS Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Ischemic (avascular) necrosis is common92 (see Chap. 211). The condition has multiple causes: endocrine or metabolic…
ECTOPIC CALCIFICATION Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Many conditions are associated with extraskeletal deposition of calcium and phosphate.4 In some, the pathogenesis is…
IDIOPATHIC OSTEOLYSIS Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Unifocal or multifocal osteolytic lesions manifest in a variety of sporadic idiopathic or hereditary disorders.87 Acro-osteolysis…
IDIOPATHIC JUVENILE OSTEOPOROSIS Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Idiopathic juvenile osteoporosis is a poorly characterized, heterogeneous condition that almost certainly has a variety…
METAPHYSEAL AND SPONDYLOMETAPHYSEAL DYSPLASIAS Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Not all disorders in children that result in widened growth plates and metaphyseal irregularity…
