Dermatologic Toxicity
Dermatologic Toxicity Susan K. Ailor Stacia C. Miles The ability of human skin to serve as a protector, a sensor, a temperature regulator, and an overall window into the body’s…
Oral Toxicity
Oral Toxicity Michael T. Brennan Rajesh V. Lalla Mark M. Schubert Douglas E. Peterson The oral cavity can be profoundly affected by cytotoxic chemotherapy used for the treatment of cancer….
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation Steven Z. Pavletic James O. Armitage Many effective cancer chemotherapeutic agents are destructive to the normal bone marrow cells. Therefore, bone marrow toxicity is often a…
Intraarterial Chemotherapy
Intraarterial Chemotherapy William D. Ensminger Intraarterial therapy is significantly more complex, difficult to correctly perform, and carries more risks than conventional standard systemic intravenous or oral therapy in the treatment…
Intraperitoneal Chemotherapy
Intraperitoneal Chemotherapy Maurie Markman The intraperitoneal administration of chemotherapeutic agents has evolved since the 1980s from a pharmacokinetic concept to a procedure that should be considered for use by physicians…
Intraventricular and Intrathecal Therapy
Intraventricular and Intrathecal Therapy Morris D. Groves Arthur D. Forman Victor A. Levin Tumor cells from almost any solid or hematologic malignancy can metastasize and come to rest in the…
Biologic Response Modifiers: Principles of Biotherapy
Biologic Response Modifiers: Principles of Biotherapy Mohamad Cherry Howard Ozer Biotherapy is one of the newest waves of cancer treatment. It uses drugs aimed at the patient’s own immune system…
Hematopoietic Growth Factors
Hematopoietic Growth Factors Jeffrey Crawford Susan Blackwell Hematopoietic growth factors are glycoproteins that stimulate the proliferation and development of clonogenic precursor cell populations. Through recombinant technology, hematopoietic growth factors administered…
Clinical Trials
Clinical Trials Jeanette A. Linebaugh WHAT ARE CLINICAL TRIALS AND WHY SHOULD THEY BE DONE? New medical knowledge can be acquired and disseminated in many ways, including case reports, collected…
Principles of Chemotherapy
Principles of Chemotherapy Carl E. Freter SINGLE AGENTS The term “chemotherapy” was coined by Paul Ehrlich in the early 20th century in a search for compounds to act as “magic…
