Oncohema Key

Factor XI Peter N. Walsh David Gailani Coagulation factor XI (FXI), previously known as plasma thromboplastin antecedent, was first identified by Rosenthal et al.1 as a deficiency in the plasma…

Structure and Function of Vitamin K-Dependent Coagulant and Anticoagulant Proteins Kanagasabai Vadivel Amy E. Schmidt Victor J. Marder Sriram Krishnaswamy S. Paul Bajaj Physiologic coagulation is initiated when, upon vascular…

Structure and Function of von Willebrand Factor Sandra L. Haberichter Robert R. Montgomery von Willebrand disease (vWD) is the most common hereditary bleeding disorder with a prevalence estimated by some…

Factor V and Factor VIII Randal J. Kaufman Philip J. Fay Laura Popolo Thomas L. Ortel Factor V and factor VIII are two homologous nonenzymatic proteins that play a critical…

Tissue Factor and the Initiation and Regulation (TFPI) of Coagulation James H. Morrissey George J. Broze Jr. Blood circulates as a liquid, but once it escapes from an injured blood…

Genetics of Coagulation Rodney M. Camire Paris Margaritis The determination of the gene, complementary deoxyribonucleic acid (cDNA), and amino acid sequences of all of the proteins known to be involved…

The Blood Coagulation Factors and Inhibitors: Their Primary Structure, Complementary DNAs, Genes, and Expression Dominic W. Chung Wenfeng Xu Earl W. Davie A BRIEF INTRODUCTION TO THE BLOOD COAGULATION CASCADE…

Overview of Basic Coagulation and Fibrinolysis Gilbert C.White II Victor J. Marder Sam Schulman William C. Aird Joel S. Bennett The development of a fibrin clot occurs after a series…

Biostatistics and Epidemiology: The Basic Science of Clinical Research Kerry L. Lee In the basic sciences, there is an essential knowledge base and an array of tools and techniques that…

Overview of the Immune System Andrew H. Lichtman The immune system is a complex collection of molecules, cells, tissues, and organs whose major function is to protect hosts from microbial…