Thrombotic and Hemorrhagic Complications Associated With Stem Cell Transplantation Yona Nadir Benjamin Brenner Thrombotic and hemorrhagic complications are common in stem cell transplantation (SCT) recipients. Endothelial cell (EC) injury is…
Myeloproliferative Neoplasms and Thrombohemorrhagic Complications Ayalew Tefferi The term “myeloproliferative disorder” (MPD) was first introduced by Dameshek1 in 1951 to emphasize the clinicopathologic interrelationship between essential thrombocythemia (ET), polycythemia vera…
The Antiphospholipid Syndrome Jacob H. Rand Lucia R. Wolgast HISTORICAL BACKGROUND The antiphospholipid syndrome (APS) is an autoimmune thrombophilic condition that is defined by a constellation of clinical and laboratory…
Vasculitides James R. Stone John H. Stone The vasculitides comprise a heterogeneous group of disorders characterized by inflammation that targets and damages blood vessels. Vasculitis may be caused by infection…
The Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndromes James N. George Thrombotic thrombocytopenic purpura (TTP)1,2 and the hemolytic uremic syndrome (HUS)3,4 were described initially as distinct disorders. Although they may…
Consumptive Thrombohemorrhagic Disorders Marcel Levi Donald I. Feinstein Robert W. Colman Victor J. Marder Known variously as disseminated intravascular coagulation (DIC), defibrination, or the consumption coagulopathies, consumptive thrombohemorrhagic disorders are…
Overview of Complex Thrombohemorrhagic Disorders Theodore E. Warkentin Victor J. Marder This overview of “complex thrombohemorrhagic disorders” emphasizes their heterogeneous clinical presentation ranging from bleeding to microvascular and macrovascular thrombosis…
Pathogenesis and Treatment of Biomaterial-Associated Thrombosis Maud B. Gorbet Michael V. Sefton Cardiovascular device manufacturers rely on elegant device designs and systemic pharmacologic agents to work wonders with existing materials…
Unusual Sites of Arterial Occlusion Philip A. Kalra Jon G. Moss Peter Wiedemann UNUSUAL SITES OF ARTERIAL OCCLUSION In this chapter, we consider occlusive arterial diseases as they affect three…
Medical and Surgical Treatment of Peripheral Arterial Disease Philip Joseph Saurabh Kalra Sonia Anand Peripheral arterial disease (PAD) affects approximately 27 million individuals in North America and Europe, and its…
