Medical Management of Differentiated Epithelial Cell Thyroid Cancer Sebastiano Filetti R. Michael Tuttle Steven I. Sherman The medical management of patients with differentiated thyroid cancer (DTC) begins following completion of…
Staging and Prognosis of Differentiated Thyroid Cancer Richard T. Kloos Introduction In the United States, the 10-year overall relative survival rates for patients with papillary thyroid cancer (PTC), follicular thyroid…
Carcinoma of the Follicular Epithelium: Surgical Therapy Gregory W. Randolph Gerard M. Doherty Introduction The management strategy for follicular cell-derived thyroid carcinoma includes operation for nearly all patients, as well…
Molecular Genetics of Tumors of Thyroid Follicular Cells James A. Fagin Yuri Efimovich Nikiforov Thyroid follicular cells give rise to tumors with distinct pathologic and clinical features. Follicular cell-derived cancers…
Carcinomas of Follicular Epithelium: Epidemiology and Pathogenesis Arthur B. Schneider Alina V. Brenner The thyroid gland is an uncommon site of cancer, accounting for only 1.4% and 4.6% new cases…
Clinical Evaluation and Management of Thyroid Nodules Susan J. Mandel Jill E. Langer Michael M. Kaplan Thyroid nodules are relatively common in adults. On physical examination of the neck, a…
Multinodular Goiter: Pathogenesis and Management Hans Graf Introduction Multinodular goiter (MNG) and diffuse goiter are defined as the enlargement of the thyroid gland, in the absence of autoimmune thyroid disease,…
Subclinical Hypothyroidism Douglas S. Ross The term “subclinical hypothyroidism” was first introduced in the early 1970s coincident with the introduction of serum thyrotropin (TSH) measurements. This term eventually replaced other…
Treatment of Hypothyroidism Jacqueline Jonklaas Historical Perspective on the Treatment of Hypothyroidism The medicinal use of animal organs, glands, and viscera originated in ancient times. Seventhcentury Chinese reportedly used both…
Diagnosis of Hypothyroidism Paul W. Ladenson Since the syndrome of myxedema was described more than a century ago, the criteria for diagnosis of hypothyroidism have evolved from clinical observation to…
