Prospective validation of clino-radio-pathological risk scoring system (CRiSS) for prediction of inguinal lymph-nodes metastasis in squamous cell carcinoma of penis

May 11, 2025 by in ONCOLOGY Comments Off on Prospective validation of clino-radio-pathological risk scoring system (CRiSS) for prediction of inguinal lymph-nodes metastasis in squamous cell carcinoma of penis

Highlights • A prospective study to validate the diagnostic performance of CRiSS in SCC penis. • CRiSS can avoid ILND with a zero false negative rate, irrespective of cN status….

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Clinical significance of PSA dynamics in castration-sensitive prostate cancer treated with ARSI doublet therapy: A multicenter study

May 11, 2025 by in ONCOLOGY Comments Off on Clinical significance of PSA dynamics in castration-sensitive prostate cancer treated with ARSI doublet therapy: A multicenter study

Highlights • The addition of androgen receptor signaling inhibitors (ARSIs) to androgen deprivation therapy (ADT), known as ARSI doublet therapy, has shown a significant impact on PSA dynamics and oncological…

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Perioperative outcomes, environmental impact and economic implications of pelvic drain discontinuation in prostate cancer patients undergoing robot-assisted radical prostatectomy

May 11, 2025 by in ONCOLOGY Comments Off on Perioperative outcomes, environmental impact and economic implications of pelvic drain discontinuation in prostate cancer patients undergoing robot-assisted radical prostatectomy

Highlights • Discontinuing pelvic drain (PD) placement after RARP did not increase the risk of overall or high-grade complications. • Patients without PD required fewer opioids, indicating better postoperative pain…

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Patient-reported functional outcomes and treatment-related regret in Hispanic and Spanish-speaking men following prostate cancer treatment

May 11, 2025 by in ONCOLOGY Comments Off on Patient-reported functional outcomes and treatment-related regret in Hispanic and Spanish-speaking men following prostate cancer treatment

Highlights • Spanish-speaking Hispanic men had no long-term adverse outcomes despite lower SES. • English-speaking Hispanic men reported higher levels of treatment-related regret. • Spanish surveys may reflect language concordant…

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Development of prediction models based on risk scores for clinically significant prostate cancer on MRI/TRUS fusion biopsy

May 11, 2025 by in ONCOLOGY Comments Off on Development of prediction models based on risk scores for clinically significant prostate cancer on MRI/TRUS fusion biopsy

Highlights • Predicting models may reduce unnecessary biopsies and optimize its indication. • Risk Scores have shown to work as reliable and ease to use predicting models. • Combining age,…

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Rethinking the definition of stage III disease in adrenocortical carcinoma: Assessing the impact of clinical lymph node positive disease

May 11, 2025 by in ONCOLOGY Comments Off on Rethinking the definition of stage III disease in adrenocortical carcinoma: Assessing the impact of clinical lymph node positive disease

Abstract Introduction Stage III adrenocortical carcinoma encompasses both lymph node positive (TanyN1M0) and negative (T3-4N0M0) disease. Given the disease’s rarity, the current staging paradigm’s estimates of survival are supported by…

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Investigating the pattern of prostate specific antigen screening among E-cigarette smokers within the behavioral risk factor surveillance system

May 11, 2025 by in ONCOLOGY Comments Off on Investigating the pattern of prostate specific antigen screening among E-cigarette smokers within the behavioral risk factor surveillance system

Highlights • E-cigarette users are less likely to undergo PSA screening than never-smokers and tobacco smokers. • This pattern of PSA screening utilization among e-cigarette users may be attributed to…

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Genetic variations related to the prostate cancer risk: A field synopsis and revaluation by Bayesian approaches of genome-wide association studies

May 11, 2025 by in ONCOLOGY Comments Off on Genetic variations related to the prostate cancer risk: A field synopsis and revaluation by Bayesian approaches of genome-wide association studies

Highlights • The calculations showed specific SNPs at 8q24 locus as noteworthy for PCa risk. • The MSMB, ITGA6, SUN2, FGF10, INCENP, MLPH, and KLK3 genes were noteworthy for PCa….

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