Statin use and oncological outcomes in a propensity-matched cohort of nonmetastatic castration resistant prostate cancer patients of the ARAMIS trial

May 11, 2025 by in ONCOLOGY Comments Off on Statin use and oncological outcomes in a propensity-matched cohort of nonmetastatic castration resistant prostate cancer patients of the ARAMIS trial

Highlights • Observational studies suggest favorable associations between statin use and prostate cancer (CaP) outcomes, data from randomized-controlled trials remain inconclusive. • We explored the relationship between statin use and…

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Risks of grade reclassification among patients with Gleason grade group 1 prostate cancer and PI-RADS 5 findings on prostate MRI

May 11, 2025 by in ONCOLOGY Comments Off on Risks of grade reclassification among patients with Gleason grade group 1 prostate cancer and PI-RADS 5 findings on prostate MRI

Highlights • Among individuals undergoing targeted biopsy of PI-RADS 5 lesions on prostate MRI, 15.2% were found to have Gleason Grade Group 1 prostate cancer. • The majority of those…

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The value of a postoperative nomogram based on the primary tumor score for overall survival of patients with renal cell carcinoma and inferior vena cava tumor thrombus

May 11, 2025 by in ONCOLOGY Comments Off on The value of a postoperative nomogram based on the primary tumor score for overall survival of patients with renal cell carcinoma and inferior vena cava tumor thrombus

Highlights • Regarding the controversy over the prognostic value of the primary tumor, our study supports that the level of IVCTT and tumor size have no significant prognostic value. •…

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Gene expression of prostate-specific membrane antigen ( FOLH1) in clear cell renal cell carcinoma predicts angiogenesis and response to tyrosine kinase inhibitors

May 11, 2025 by in ONCOLOGY Comments Off on Gene expression of prostate-specific membrane antigen ( FOLH1) in clear cell renal cell carcinoma predicts angiogenesis and response to tyrosine kinase inhibitors

Highlights • Combination systemic therapies (STs) including immuno-oncologic (IO) and VEGF-inhibiting (VEGFi) agents, predominantly tyrosine kinase inhibitors (TKI), have become the standard of care for metastatic clear cell carcinoma. •…

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