Abstract Prostate specific antigen (PSA) has transformed the diagnosis and treatment of prostate cancer by enabling early detection at global scale. Due to expression in both benign and malignant cells,…
Highlights • Family history of prostate cancer is an important risk factor of being diagnosed with the disease, even in the setting of low PSA. • Black men are at…
Highlights • Randomized trials show PSA screening decreases prostate cancer-mortality. • Adjunct tests and focus on high-risk patients will improve prostate cancer screening. • A closer look at divergence in…
Highlights • Prostate specific antigen is a proven screening test that has reduced prostate cancer mortality. • A desire to improve the positive and negative predictive values of PSA has…
Abstract Prostate cancer (PCa) screening has evolved beyond PSA and digital rectal exam to include multiparametric prostate MRI (mpMRI). Incorporating this advanced imaging tool has further limited the well-established problem…
