Testicular cancer malpractice trends
Highlights • A review of malpractice cases involving testicular cancer patients was performed. • About 24 malpractice cases were identified, the majority of which were related to delayed diagnosis. •…
Impact of heavy metals, oxidative stress, expression of VHL, and antioxidant genes in the pathogenesis of renal cell carcinoma
Highlights • Blood and urine heavy metals were increased in patients with RCC compared to healthy controls. • Serum oxidation markers revealed reduced antioxidation and increased pro-oxidant enzyme levels in…
Testosterone recovery after androgen deprivation therapy
Highlights • Testosterone recovery after androgen deprivation therapy is highly variable. • Younger age and GnRH antagonist use are associated with testosterone recovery. • Many men prescribed GnRH agonists may…
The prognostic significance of circulating tumor DNA in patients with positive lymph node disease after robotic-assisted radical cystectomy: A contemporary analysis
Highlights • Patients with Lymph node positive disease after radical cystectomy with extended lymphadenectomy fare worse than patients with lymph node negative disease. • Patients with pN1 disease didn’t differ…
Short and long-term outcomes of arterial and caval replacement during postchemotherapy retroperitoneal lymph node dissection in metastatic testicular cancer
Highlights • The overall survival rate for patients undergoing PC-RPLND with resection of the aorta, IVC, and/or iliac artery is 45% at 2 years. • Among 41 men undergoing complex…
Natural history of PIRADS-2 lesions on serial multiparametric magnetic resonance imaging: Real-life data from an Academic Center
Highlights • Serial mpMRI scans revealed upgrade to PIRADS≥3 in 31.4≥ cases with a PIRADS-2 index lesion. • A PSA increase of ≥25% during follow-up was the only predictor of…
Intraoperative margin assessment with near real time pathology during partial gland ablation of prostate cancer: A feasibility study
Highlights • Stimulated Raman histology can be interpreted by humans and artificial intelligence. • Stimulated Raman histology can provide procedural tumoral mapping during cryosurgical ablation of prostate cancer. • Stimulated…
Prevalence and management of castration-resistant prostate cancer of unknown metastatic status in the real-world setting: The AfroDiTA study
Highlights • Of PC patients on continuous ADT in Spain, 4.8% had CRPC with unknown metastatic status (MX). • Most CRPC-MX patients had not been treated with curative intent at…
The learning curve for transperineal MRI/TRUS fusion prostate biopsy: A prospective evaluation of a stepwise approach
Highlights • MRI/TRUS fusion TP PBx clinically significant prostate cancer detection rates were consistent across the chronological quintiles. • Procedure time significantly reduced from a median of 46 to 19…
Development and validation of a clinic-radiomics model based on intratumoral habitat imaging for progression-free survival prediction of patients with clear cell renal cell carcinoma: A multicenter study
Highlights • The hybrid model designed in this study could serve as an alternative tool for noninvasive progression-free survival prediction of ccRCC patients. • The predictive performance of habitat imaging-based…
