Biological Basis of Radiotherapy of the Breast
Abstract Radiation therapy is commonly used in early-stage breast cancer treatment but must be delivered carefully to minimize the risks to critical adjacent structures, such as the heart and lung….
Postmastectomy Radiotherapy
Abstract Postmastectomy radiotherapy (PMRT) is an integral component of the multimodal treatment of invasive breast cancer in patients with sufficient risk of harboring a reservoir of locoregional disease despite mastectomy…
Radiotherapy and Ductal Carcinoma in Situ
Abstract Multiple retrospective studies and prospective randomized trials have clearly established the long-term efficacy of breast conserving surgery and radiotherapy in the management of patients with DCIS. Radiation therapy has…
Breast Imaging Screening and Diagnosis
Abstract This chapter reviews the most commonly used imaging modalities in the screening and diagnosis of breast diseases. Topics discussed include characteristic benign and malignant imaging findings on mammography, breast…
General Principles of Mastectomy: Evaluation and Therapeutic Options
Abstract Although conservative breast surgery is favored for the treatment of early stage breast cancer, mastectomy still has a place in the armamentarium of the surgeon. In the case of…
Assessment and Designation of Breast Cancer Stage
Abstract Staging of breast cancer is critical for making treatment decisions as well as for prognosis. Staging systems have evolved over time, and most providers caring for patients with breast…
Breast Reconstruction and Oncoplastic Surgery
Abstract Just as the surgical management of breast cancer has evolved, so too has the field of breast surgery. Patient and surgeon expectations are no longer limited to recreating a…
The New Paradigm: Oncoplastic Breast Conservation Surgery
Abstract Standard breast preservation techniques often fail to achieve the desired goal of complete tumor extirpation with adequate margins while preserving breast cosmesis. The emergence of oncoplastic breast surgery addresses…
Lobular Carcinoma in Situ of the Breast
Abstract Lobular carcinoma in situ (LCIS) exists as two main subtypes, classic and pleomorphic. While it may sometimes be an invasive cancer precursor, LCIS can be treated as a risk…
Ductal Carcinoma in Situ of the Breast
Abstract Ductal carcinoma in situ (DCIS) of the breast is a heterogeneous group of lesions with diverse malignant potential and a range of treatment options. It is the most rapidly…
