Treatment of Metastatic Pancreatic Cancer
BACKGROUND AND INTRODUCTION Print Section Listen Pancreatic cancer is a devastating disease that presents late and is fatal in nearly all cases. It affects about 12 per 100,000 men and…
Systemic and Regional Therapy for Pancreatic Neuroendocrine Tumors
INTRODUCTION Print Section Listen Pancreatic neuroendocrine tumors (PNETs) are thought to arise from mature endocrine cells in the pancreas and/or pleuripotent stem cells that have the capacity to differentiate into…
Clinical and Pathologic Staging for Pancreatic Cancer
INTRODUCTION Print Section Listen Cancer staging systems have been designed to provide both physicians and patients with a metric for assessing the extent of disease and prognosis. Staging systems provide…
Natural History and Principles of Management of Pancreatic Neuroendocrine Tumors
INTRODUCTION Print Section Listen Pancreatic neuroendocrine tumors (PNETs) are tumors that originate from the islet cells of the pancreas and are also often referred to as islet cell tumors. With…
Pancreatic Cancer: Principles of Pancreaticoduodenectomy and Distal Pancreatectomy
INTRODUCTION Print Section Listen Pancreatic ductal adenocarcinoma (PDA) is the fourth leading cause of cancer-related deaths in the United States and the eighth worldwide. Despite advances in medical therapy, survival…
Principles of Palliative Care for Patients with Pancreatic Adenocarcinoma
INTRODUCTION Print Section Listen Palliative care is an approach to care that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through…
Multidisciplinary Management of Pancreatic Cancer
INTRODUCTION Print Section Listen Background The treatment of cancer patients has become complex as a result of the introduction of new therapies and insights into how to use these therapies….
Molecular Genetics of Pancreatic Neoplasms and Inherited Pancreatic Cancer Syndromes
INTRODUCTION Print Section Listen Cancer is fundamentally a genetic disease that develops when alterations in multiple genes result in dysregulation of a select number of cellular pathways and processes. In…
Gallbladder Cancer
GENERAL CONSIDERATIONS Print Section Listen Gallbladder cancer is an aggressive malignancy with a generally poor prognosis. Described for the first time in two autopsy cases by Stoll and his colleagues…
Perihilar Cholangiocarcinoma
OVERVIEW Print Section Listen Cholangiocarcinoma is a diverse group of rare but highly fatal malignancies arising from the biliary tract epithelium. According to their anatomical origin in the biliary tract,…
