INTRODUCTION Print Section Listen This chapter describes the indications for surgery, technical aspects of surgery, and outcomes for patients with metastatic melanoma involving regional lymph nodes (stage III) or distant…
TREATMENTS DIRECTED AT LOCOREGIONAL RECURRENCE AND IN-TRANSIT METASTASES Print Section Listen Locoregional recurrence of a melanoma is defined as recurrence in or around a scar from previous melanoma surgery, or…
INTRODUCTION Print Section Listen Sentinel lymph node (SLN) biopsy is now a standard component of the treatment of many melanomas, and its use is accepted as routine.1,2 So routine, in…
BIOPSY Print Section Listen A skin lesion that is suspicious for melanoma is best removed by excisional biopsy with a 1- to 2-mm clinical lateral margin and a deep margin…
INTRODUCTION Print Section Listen Regional cancer therapies are treatments that direct a therapeutic intervention to a cancer burdened organ or region of the body; they have the collective advantage of…
INTRODUCTION Print Section Listen Cancer is a complex disease capable of manifesting itself as many different disease phenotypes occurring in virtually any tissue of the body. This complexity can be…
“EPIGENETICS”: ORIGIN OF THE WORD Print Section Listen Conrad Hal Waddington is usually credited with modifying the Greek word “epigenesis,” which described a theory of development, into a new term…
EXTERNAL BEAM RADIATION THERAPY Print Section Listen Radiation Oncology is the medical discipline that uses ionizing radiation with therapeutic intent in the management of cancer and selected benign disease. Compared…
BACKGROUND Print Section Listen Chemotherapy has been the mainstay of systemic treatment of cancer for nearly 75 years. Chemotherapy can be broadly classified as either cytotoxic (killing rapidly dividing cells)…
