Follicular Thyroid Carcinoma
BACKGROUND Print Section Listen Historically, practice guidelines and various medical resources have combined follicular thyroid cancer (FTC) with papillary thyroid cancer (PTC) as if they were a single entity of…
Multiple Endocrine Neoplasia Type 1
BACKGROUND Print Section Listen The multiple endocrine neoplasia type 1 (MEN1) syndrome was initially described in 1954 as Wermer’s syndrome. Dr Paul Wermer reported on a syndrome in which adenomatosis…
Parathyroid Carcinoma
INTRODUCTION Print Section Listen Parathyroid carcinoma is a rare malignant neoplasm of the parathyroid causing parathyroid hormone (PTH)–dependent hypercalcemia. Diagnosis is difficult so a high level of suspicion must be…
Medullary Thyroid Cancer
BACKGROUND Print Section Listen Medullary thyroid cancer (MTC) is a well-differentiated neuroendocrine tumor arising from the calcitonin-producing parafollicular cells, also known as C cells. C cells are derived from neural…
Thyroid Nodules
INTRODUCTION Print Section Listen Thyroid nodules are a commonly encountered clinical entity. Although the majority of thyroid nodules are benign, the risk of malignancy necessitates a thorough evaluation and workup….
Locally Advanced and Aggressive Thyroid Cancer
INTRODUCTION Print Section Listen Thyroid cancer is considered to be the most common endocrine malignancy, with estimated new cases exceeding 60,000 in 2013.1 Although most patients who present with thyroid…
Basal Cell Carcinoma
BACKGROUND Print Section Listen Basal cell carcinoma (BCC) is the most common malignancy afflicting mankind. Sometimes referred to as a rodent ulcer, the tumor was recognized by the Egyptians, Greeks,…
Extremity and Trunk Sarcomas
INTRODUCTION Print Section Listen “Nature often gives us hints to her profoundest secrets, and it is possible that she has given us a hint which, if we will but follow,…
Uncommon Cutaneous Malignancies
INTRODUCTION Print Section Listen The management of uncommon and rare cutaneous malignancies can be challenging due the lack of high-quality evidence for guidance. They include a varied group of skin…
Metastatic Sarcoma
INTRODUCTION Print Section Listen Among individuals diagnosed with bone or soft tissue sarcoma, approximately 10% will have metastatic disease at the time of presentation,1–6 and an estimated 40% will develop…
