Mastectomy and Breast Reconstruction

Jan 6, 2019 by in ONCOLOGY Comments Off on Mastectomy and Breast Reconstruction

HISTORICAL PERSPECTIVE Print Section Listen Mastectomy has been utilized in the surgical management of patients with breast cancer for centuries. It was William Stewart Halsted who popularized the technique of…

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Screening for Breast Cancer

Jan 6, 2019 by in ONCOLOGY Comments Off on Screening for Breast Cancer

INTRODUCTION Print Section Listen Breast cancer remains the most common cancer in American women, excluding cancers of the skin, and accounts for 29% of all female cancer in the United…

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Lobular Carcinoma in Situ and Lobular Neoplasia

Jan 6, 2019 by in ONCOLOGY Comments Off on Lobular Carcinoma in Situ and Lobular Neoplasia

BACKGROUND Print Section Listen The term lobular neoplasia (LN) encompasses the entire spectrum of atypical epithelial lesions that originate in the terminal duct-lobular unit (TDLU) of the breast, and are…

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Radiation Therapy for High-Risk Breast Cancer

Jan 6, 2019 by in ONCOLOGY Comments Off on Radiation Therapy for High-Risk Breast Cancer

INTRODUCTION Print Section Listen Radiotherapy is utilized as a part of breast-conserving therapy (lumpectomy followed by radiation therapy) or as an adjuvant therapy to mastectomy. This chapter focuses on recommendations…

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Local Therapy in the Setting of Metastatic Disease

Jan 6, 2019 by in ONCOLOGY Comments Off on Local Therapy in the Setting of Metastatic Disease

BACKGROUND Print Section Listen Approximately 3.5% to 4% of women with newly diagnosed breast cancer are found to have stage IV disease at presentation according to the Surveillance, Epidemiology, and…

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Management of the Pathologically Positive Axilla

Jan 6, 2019 by in ONCOLOGY Comments Off on Management of the Pathologically Positive Axilla

INTRODUCTION Print Section Listen A generally accepted tenet of management of solid tumor malignancies—including adenocarcinoma of the breast—is that most bulky/clinically evident sites of disease are best managed by surgical…

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Cancer of the Oral Cavity

Jan 6, 2019 by in ONCOLOGY Comments Off on Cancer of the Oral Cavity

INTRODUCTION Print Section Listen The oral cavity is the most common site for squamous cell carcinoma (SCC) of the head and neck, a disease that inflicts substantial morbidity and mortality…

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High-Risk Breast Pathology

Jan 6, 2019 by in ONCOLOGY Comments Off on High-Risk Breast Pathology

SYNOPSIS Print Section Listen The phrase “high-risk breast pathology” has two meanings. Classically, it refers to specific histologic findings in breast biopsy tissue that portend an increased risk of breast…

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Skin Cancer of the Head and Neck

Jan 6, 2019 by in ONCOLOGY Comments Off on Skin Cancer of the Head and Neck

INTRODUCTION Print Section Listen Skin cancer of the head and neck is a heterogeneous group of malignancies that together constitute the most common cancer of this anatomic region. The majority…

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Surgical Strategies for Breast Cancer Risk Reduction

Jan 6, 2019 by in ONCOLOGY Comments Off on Surgical Strategies for Breast Cancer Risk Reduction

INTRODUCTION Print Section Listen Surgical prophylaxis remains the most effective means to prevent breast cancer. Strategies for risk reduction include bilateral prophylactic mastectomy (BPM), contralateral prophylactic mastectomy (CPM), and prophylactic…

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