Apoptosis Induction and Regulation
(1) Institut Bergonié, Bordeaux, France Abstract Apoptosis is one of the main modalities of cell death, so important that it has outshined all others that only begin to be…
Cell Cycle Control
(1) Institut Bergonié, Bordeaux, France Abstract Cell cycle consists of the sequential events occurring between the emergence of a new cell and that of the two daughter cells generated…
Signalling by Oxygen and Nitric Oxide
(1) Institut Bergonié, Bordeaux, France Abstract Oxygen is, first of all, the combustive agent required for life and the provider of energy required by all heterotrophic organisms, those which…
Phosphatidylinositol 3-Kinase Pathway
(1) Institut Bergonié, Bordeaux, France Abstract The phosphatidylinositol 3-kinase (PI3K) pathway is one of the signalling pathways activated following the interaction of a growth factor with a tyrosine kinase…
Growth Factors and Tyrosine Kinase Receptors
(1) Institut Bergonié, Bordeaux, France Abstract Signalling pathways originating from the interaction between growth factors (GF) and tyrosine kinase receptors (TKRs) are certainly the best known because of their…
Toll-Like Receptors, Interleukin 1 and NFκB
(1) Institut Bergonié, Bordeaux, France Abstract Toll-like receptors (TLR) constitute a family of receptors involved in immune and inflammatory processes, which recognise molecules derived from infectious agents (bacteria, viruses)…
G-Protein-Coupled Receptors
(1) Institut Bergonié, Bordeaux, France Abstract G-protein-coupled receptors (GPCRs) constitute a huge family of membrane receptors to numerous hormones, neurotransmitters and diverse compounds. A large part of cardiovascular and…
Nuclear Receptor Pathways
(1) Institut Bergonié, Bordeaux, France Abstract Nuclear receptors constitute a special class of transcription factors that are activated by an extracellular signal. This signal is a hydrophobic substance, such…
MAP Kinase Pathway
(1) Institut Bergonié, Bordeaux, France Abstract The MAP kinase pathway (or, better, the MAP kinase pathways) is certainly one of the main proliferation pathways, the best known and the…
