This article summarizes the current literature in treatment of unresectable biliary tract and primary liver tumors. Locoregional therapies including radiofrequency ablation, percutaneous ethanol injection, cryoablation, microwave ablation, transarterial chemoembolization, hepatic…
Tumors of the biliary tract and hepatocellular carcinoma (HCC) are complex tumors with heterogeneous carcinogenic mechanisms. Patients with hepatobiliary cancer have advances disease and need systematic therapy to palliate symptoms…
Radiation therapy is emerging as a potentially effective treatment of locally advanced, unresectable hepatocellular carcinoma (HCC). Outcomes from early prospective studies seem promising, with improved survival compared with historical controls….
Over the last decade, transarterial therapies have gained worldwide acceptance as standard of care for inoperable primary liver cancer. Survival times after transarterial chemoembolization (TACE) continue to improve as the…
For patients with hepatobiliary malignancies, various therapeutic options are currently available. To optimize the selection of these treatment options, adequate stratification of patients according to their prognosis is practically important….
The successful management of hepatocellular carcinoma (HCC) requires a multidisciplinary approach, incorporating hepatologists, oncologists, surgical oncologists, transplant surgeons, and radiologists. With improvements in technology and better long-term outcomes data, management…
Optimal treatment of hilar cholangiocarcinoma depends on location of the cancer and extent of biliary and vascular involvement. Candidates for resection or transplantation must be evaluated and managed by a…
Distal cholangiocarcinoma is an uncommon malignancy and early diagnosis remains a challenge. More accurate diagnostic modalities for early-stage diagnosis are needed. Advances in medical therapy and neoadjuvant treatment may aid…
Intrahepatic cholangiocarcinoma (ICC) is a rare tumor, with an increasing incidence worldwide and an overall poor prognosis. Symptoms are usually nonspecific, contributing to an advanced tumor stage at diagnosis. The…
Advances in percutaneous and endoscopic techniques have improved preoperative selection and optimization in patients with biliary and liver tumors, but are not without their own controversies. Selective rather than routine…
