Targeting Hypoxic Adaptations of Cancer Cells: Molecular Mechanisms and Therapeutic Opportunities
Fig. 14.1 Mechanisms of hypoxia-inducible factor (HIF)-1α regulation under aerobic and hypoxic conditions. VHL von Hippel-Lindau 14.3 The Role of HIF-1 in Tumorigenesis Data from genome-wide chromatin immunoprecipitation coupled to…