Methods in Mathematical Modeling for Stem Cells
(18.1) with the initial condition P(t 0) = P 0, where M, δ, γ and θ are parameters. We refer to the model (18.1) as the hyperbolastic ordinary differential equation of type…
Molecular and Functional Characterization of Human Adipocytes
Fig. 20.1 Electron microscopy analysis. Mature adipocyte has thin cytoplasm and a nucleus characteristically squeezed by the large lipid vacuoles. The cytoplasmatic organelles are poorly represented. Scale bar = 4 μm To…
Soluble CD40L in Stem Cell Products
Fig. 21.1 Semiquantitative analysis of MMP-2- and MMP-9-concentrations by determining the optical densities of a respective zymogram using peripheral blood of allogenic stem cell donors (n = 6) before and after GM-GCSF-stimulation…
Induced Pluripotent Stem Cells Differentiate into Functional Cardiomyocytes
(1) Department of Cardiothoracic, Transplantation and Vascular Surgery, Leibniz Research Laboratories for Biotechnology and Artificial Organs, REBIRTH – Center for Regenerative Medicine (OE 6217), Hannover Medical School, Carl-Neuberg-Str. 1, HBZ…
Improved Renal Revascularization Outcomes in Pigs Using Stem Cells
Fig. 13.1 BOLD parametric map in normal, RAS, RAS+PTRA, and RAS+PTRA+EPC pigs 10 weeks after RAS and 4 weeks after revascularization. Stenotic RAS kidneys show greater distribution of cortical green…
Preoptic Regulatory Factor-2, a Rhogap Domain Protein that Modifies Cell Cycle Progression and Apoptosis in the CNS
Fig. 19.1 The Rho GTPase cycle of activation and inactivation. Rho GTPases in the inactive GDP-bound conformation can be converted to the active state by the GEF family of proteins….
Overcoming Radioresistance of Lung Cancer Stem Cells
Fig. 11.1 Schematic illustrating the cellular organization in the human adult lung. (a) The architecture of the proximal airway epithelium in the trachea, bronchi, and bronchioles. (b) The airway epithelium…
Characteristics of Satellite Cells and Multipotent Adult Stem Cells in the Skeletal Muscle
Fig. 6.1 Regulation of the developmental program of satellite cells. (a) Schematic illustrating the myogenic lineage progression. Satellite stem cells are marked by the expression of Pax7, but have never…
Repairing the Stroke-Damaged Brain: From Neural Stem Cells to Tissue Engineering
Fig. 16.1 Endogenous neural stem cells and stroke. (a) Stroke invokes a neurobiological response in the affected tissue that is diverse by involving different types of cells, such as astrocytes…
Generation of Autologous Multipotent Endothelial-Like Cells from Lipoaspirates of Human Adipose-Derived Stem Cells and Polymer Microarrays Technology: Potential Cardiovascular Regeneration
Fig. 14.1 Culture and differentiation of ME-LCs. hASCs were obtained from liposuction procedure. These cells were cultured along different stages in diverse media: DMEM-FBS (stage I), DMEM free-serum (stage II),…
