Neuropsychological Late Effects of Radiotherapy for Pediatric Brain Tumors
Neurocognitive domain Intellectual/global cognitive functioning Academic achievement Visuospatial and motor Attention and working memory Memory Processing speed Executive functioning Measurement instrument WISC Full Scale IQ WJ-Achievement WISC Perceptual Reasoning…
Reirradiation
Author technique year Median PFS post RT2 Median OS post RT2 Median PFS No RT2 Median OS No RT2 Merchant FFRT 2008 NA 67% at 5 years NA NA Merchant CSI…
Special Radiation Techniques for Pediatric Brain Tumors: Hypofractionation, Radiosurgery, and Brachytherapy
© Springer International Publishing AG 2018Anita Mahajan and Arnold Paulino (eds.)Radiation Oncology for Pediatric CNS Tumorshttps://doi.org/10.1007/978-3-319-55430-3_28 28. Special Radiation Techniques for Pediatric Brain Tumors: Hypofractionation, Radiosurgery, and Brachytherapy Susan M. Hiniker1 and Iris C. Gibbs1 (1) Department of Radiation…
Supratentorial Primitive Neuroectodermal Tumor
Fig. 7.1 Representative axial images from MRI of a 4-year-old patient with SPNET. On non-contrast T1-weighted (a), T2-weighted (b), and fluid-attenuated inversion recovery (FLAIR, c) images, tumor has isointense signal…
Medulloblastoma
Fig. 6.1 Molecular subgroups of medulloblastoma. Four molecular subgroups have been identified in children. The patient demographic and tumor characteristics are presented (Taylor et al. 2012) 6.5 Workup Children with…
Chemotherapeutic Strategies in Brain Tumors
• Intrathecal administration • Convection enhanced delivery • Blood Brain Barrier disruption • Intra-arterial administration • Intratumoral delivery Intrathecal administration of drugs like Ara-C and mafosfamide has been used in medulloblastoma, pineoblastoma, and recurrent brain…
Conformal Radiation Therapy for Pediatric CNS Tumors
Fig. 25.1 A non-coplanar 3DCRT plan on left shows a less conformal prescription dose distribution around the concave PTV in red. An IMRT plan is more conformal around the PTV…
Anesthesia for Immobilization
© Springer International Publishing AG 2018Anita Mahajan and Arnold Paulino (eds.)Radiation Oncology for Pediatric CNS Tumorshttps://doi.org/10.1007/978-3-319-55430-3_23 23. Anesthesia for Immobilization Pascal Owusu-Agyemang1 (1) Department of Anesthesiology, The University of Texas MD Anderson Cancer Center, Houston, TX,…