COMPLICATIONS OF BRAIN IRRADIATION Part of “CHAPTER 22 – RADIOTHERAPY OF PITUITARYHYPOTHALAMIC TUMORS“ Modern megavoltage radiotherapy produces minimal acute toxicity, including temporary alopecia, mild dermatitis, and a serous otitis media…
HYPOTHALAMIC NEOPLASMS Part of “CHAPTER 22 – RADIOTHERAPY OF PITUITARYHYPOTHALAMIC TUMORS“ GERMINOMA Germinomas typically arise in the floor of the third ventricle and have a propensity to invade and compress…
CRANIOPHARYNGIOMAS Part of “CHAPTER 22 – RADIOTHERAPY OF PITUITARYHYPOTHALAMIC TUMORS“ Craniopharyngiomas are relatively rare neoplasms that arise from epithelial remnants of the Rathke pouch and are typically found in the…
PITUITARY ADENOMAS Part of “CHAPTER 22 – RADIOTHERAPY OF PITUITARYHYPOTHALAMIC TUMORS“ The role of radiotherapy in the management of pituitary adenomas remains poorly defined because of several factors, including the…
RADIOTHERAPY OF PITUITARYHYPOTHALAMIC TUMORS Minesh P. Mehta Radiotherapeutic management of pituitary adenomas and tumors of the hypothalamus requires a thorough understanding of the various hypersecretory syndromes and their wide spread…
HYPERSECRETION OF THYROID-STIMULATING HORMONE Part of “CHAPTER 21 – MEDICAL TREATMENT OF PITUITARY TUMORS AND HYPERSECRETORY STATES“ THYROID-STIMULATING HORMONE–SECRETING ADENOMA The rare patients who have TSH-secreting adenoma present with increased…
GONADOTROPIN HYPERSECRETION Part of “CHAPTER 21 – MEDICAL TREATMENT OF PITUITARY TUMORS AND HYPERSECRETORY STATES“ GONADOTROPIN-SECRETING ADENOMAS The standard therapy for gonadotropin-secreting adenomas is surgical resection, often followed by radiation…
GROWTH HORMONE HYPERSECRETION Part of “CHAPTER 21 – MEDICAL TREATMENT OF PITUITARY TUMORS AND HYPERSECRETORY STATES“ Transsphenoidal surgery remains the treatment of choice for growth hormone–secreting adenomas (see Chap. 23)….
ADRENOCORTICOTROPIC HORMONE HYPERSECRETION Part of “CHAPTER 21 – MEDICAL TREATMENT OF PITUITARY TUMORS AND HYPERSECRETORY STATES“ When Cushing syndrome is caused by a pituitary tumor (Cushing disease), transsphenoidal surgery is…
PROLACTIN HYPERSECRETION Part of “CHAPTER 21 – MEDICAL TREATMENT OF PITUITARY TUMORS AND HYPERSECRETORY STATES“ MICROPROLACTINOMAS In women with microprolactinomas (tumor diameter of <10 mm) who require therapy for menstrual…
