Oncohema Key

BONE QUANTIFICATION AND DYNAMICS OF TURNOVER David W. Dempster Elizabeth Shane The period since the 1970s has produced tremendous growth in the understanding of the pathophysiology of bone. This has…

ASSESSMENT OF VITAMIN D STATUS Part of “CHAPTER 54 – VITAMIN D“ Because of the wide anatomic distribution of the sites of synthesis, metabolism, and action of vitamin D, clinical…

MEASUREMENT OF VITAMIN D METABOLITES Part of “CHAPTER 54 – VITAMIN D“ METHODS The measurement of vitamin D in biologic fluids was pioneered with bioassays that measured either the linear…

BIOLOGIC ACTIONS OF VITAMIN D Part of “CHAPTER 54 – VITAMIN D“ INTESTINE CALCIUM TRANSPORT The most important bioeffect of 1,25(OH)2D3 is to increase the intestinal absorption of calcium. Although…

REGULATION OF VITAMIN D METABOLISM Part of “CHAPTER 54 – VITAMIN D“ The metabolic activation of vitamin D is subject to both coarse-and fine-control mechanisms operating at the principal enzymatic…

CHEMISTRY Part of “CHAPTER 54 – VITAMIN D“ Vitamin D and its analogs form a group of fat-soluble secosterols with antirachitic properties.1 The two parent forms of vitamin D are…

VITAMIN D Thomas L. Clemens Jeffrey L. H. O’Riordan CHEMISTRY PRODUCTION AND METABOLISM OF VITAMIN D

CONCLUSION Part of “CHAPTER 53 – CALCITONIN GENE FAMILY OF PEPTIDES“

RECEPTORS OF THE CALCITONIN GENE FAMILY OF PEPTIDES Part of “CHAPTER 53 – CALCITONIN GENE FAMILY OF PEPTIDES“ The peptides of the CT-gene family exert their bioeffects through binding to…

ADRENOMEDULLIN Part of “CHAPTER 53 – CALCITONIN GENE FAMILY OF PEPTIDES“ ADM, originating from the CALC-V gene (see Fig. 53-1 and Fig. 53-2), is a 52-amino-acid peptide originally isolated from…