OSTEOPETROSIS

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on OSTEOPETROSIS

OSTEOPETROSIS Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Osteopetrosis (marble bone disease) is one of many disorders that cause high bone mass (Table 66-1).6 Two…

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TREATMENT

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on TREATMENT

TREATMENT Part of “CHAPTER 65 – PAGET DISEASE OF BONE“ Issues regarding therapy for Paget disease include questions about the indications for specific medical treatment, anticipated benefits from these treatments,…

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DIAGNOSIS

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on DIAGNOSIS

DIAGNOSIS Part of “CHAPTER 65 – PAGET DISEASE OF BONE“ The diagnosis of Paget disease is based on a combination of the medical history and physical examination (particularly when increased…

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CLINICAL PRESENTATION

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on CLINICAL PRESENTATION

CLINICAL PRESENTATION Part of “CHAPTER 65 – PAGET DISEASE OF BONE“ The localized nature of Paget disease leads to a variable clinical presentation. Frequently, only one or two bones are…

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PATHOLOGY

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on PATHOLOGY

PATHOLOGY Part of “CHAPTER 65 – PAGET DISEASE OF BONE“ The initial abnormality in Paget disease is a marked increase in the rate of bone resorption at localized sites, mediated…

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ETIOLOGY

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on ETIOLOGY

ETIOLOGY Part of “CHAPTER 65 – PAGET DISEASE OF BONE“ The precise etiology of Paget disease remains unknown; genetic and environmental—specifically viral—factors play a role. Geographic and ethnic epidemiologic data…

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PAGET DISEASE OF BONE

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on PAGET DISEASE OF BONE

PAGET DISEASE OF BONE Ethel S. Siris Paget disease of bone is a localized disorder of skeletal remodeling in which abnormally increased rates of both bone resorption and new bone…

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OTHER OSTEOLYTIC SYNDROMES

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on OTHER OSTEOLYTIC SYNDROMES

OTHER OSTEOLYTIC SYNDROMES Part of “CHAPTER 64 – OSTEOPOROSIS“ A number of rare syndromes can lead to some degree of bone lysis. These osteolytic syndromes can result from infectious, neoplastic,…

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OTHER FORMS OF PRIMARY OSTEOPOROSIS

Aug 25, 2016 by in ENDOCRINOLOGY Comments Off on OTHER FORMS OF PRIMARY OSTEOPOROSIS

OTHER FORMS OF PRIMARY OSTEOPOROSIS Part of “CHAPTER 64 – OSTEOPOROSIS“ OSTEOPOROSIS IN MEN Although osteoporosis is more common in women, it is not unusual in men. One-fifth of all…

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