DISTRIBUTION IN THE CIRCULATION
DISTRIBUTION IN THE CIRCULATION Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ Substantial variability exists in the production rate of the various steroids by males and females (see…
REGULATION OF ADRENAL CORTICOSTEROID PRODUCTION
REGULATION OF ADRENAL CORTICOSTEROID PRODUCTION Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ CORTISOL SECRETION ADRENOCORTICOTROPIC HORMONE ACTH is a 39-amino-acid peptide that is produced in the anterior…
BIOSYNTHESIS
BIOSYNTHESIS Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ IMPORTATION INTO MITOCHONDRIA The rate-limiting step in steroid biosynthesis is importation of cholesterol from cellular stores to the matrix…
STRUCTURE AND NOMENCLATURE
STRUCTURE AND NOMENCLATURE Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ Steroids have a common structure with 17-carbon atoms arranged in three six-membered rings and a fourth five-membered…
SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS
SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS Perrin C. White The adrenal glands are endocrinologically complex organs that are composed of two distinct endocrine tissues derived from different embryologic sources1 (see Chap….
HISTOPATHOLOGY OF THE ADRENAL MEDULLA
HISTOPATHOLOGY OF THE ADRENAL MEDULLA Part of “CHAPTER 71 – MORPHOLOGY OF THE ADRENAL CORTEX AND MEDULLA“ NORMAL HISTOLOGY The medulla is located primarily in the head of the adrenal…
HISTOPATHOLOGY OF THE ADRENAL CORTEX
HISTOPATHOLOGY OF THE ADRENAL CORTEX Part of “CHAPTER 71 – MORPHOLOGY OF THE ADRENAL CORTEX AND MEDULLA“ NORMAL HISTOLOGY The adult adrenal cortex includes the outer 80% of the adrenal…
EMBRYOLOGY
EMBRYOLOGY Part of “CHAPTER 71 – MORPHOLOGY OF THE ADRENAL CORTEX AND MEDULLA“ The adrenal cortex and medulla arise from separate embryologic tissues (Fig. 71-1). Beginning in the fourth week…
