TESTS FOR THE DIFFERENTIAL DIAGNOSIS OF HYPERCORTISOLISM Part of “CHAPTER 74 – TESTS OF ADRENOCORTICAL FUNCTION“ The traditional differential diagnostic tests for adrenal hyper-function, which focus on establishing the presence…
TESTS FOR DOCUMENTING HYPERCORTISOLISM Part of “CHAPTER 74 – TESTS OF ADRENOCORTICAL FUNCTION“ URINARY FREE CORTISOL Urinary free cortisol is cortisol in urine that is not conjugated to amino acids…
TESTS OF ADRENOCORTICAL FUNCTION D. Lynn Loriaux The diagnosis of adrenocortical disease depends on accurate and precise laboratory measurements. The optimal application of the available tests is an evolving process….
ACTIONS OF THE ADRENAL ANDROGENS Part of “CHAPTER 73 – CORTICOSTEROID ACTION“ Many actions of adrenal androgens are exerted through their conversion to active androgens or estrogens such as testosterone,…
ACTIONS OF THE MINERALOCORTICOIDS Part of “CHAPTER 73 – CORTICOSTEROID ACTION“ In order of decreasing potency, the mineralocorticoids include aldosterone, 11-deoxycorticosterone, 18-oxocortisol, corticosterone, and cortisol. As a class of hormones,…
ACTIONS OF THE GLUCOCORTICOIDS Part of “CHAPTER 73 – CORTICOSTEROID ACTION“ Glucocorticoids are essential for survival. The term glucocorticoid refers to the glucose-regulating properties of these hormones. However, the glucocorticoids…
GENERAL MECHANISMS OF ACTION Part of “CHAPTER 73 – CORTICOSTEROID ACTION“ The steroid hormones, vitamin D, retinoic acid, and the thyroid hormones all share a similar mechanism of action.1,2 These…
CORTICOSTEROID ACTION Perrin C. White GENERAL MECHANISMS OF ACTION Related posts: REGULATION OF THE GROWTH HORMONE RECEPTOR AND BINDING PROTEIN GONADOTROPE ADENOMAS OF THE PITUITARY PROLACTIN HYPERSECRETION DEFINITIONS THYROID-HORMONE RECEPTOR…
METABOLISM Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ The liver and the kidney are the principal organs involved in clearing the steroid hormones from the circulation. Although…
ALTERATIONS IN BINDING PROTEINS Part of “CHAPTER 72 – SYNTHESIS AND METABOLISM OF CORTICOSTEROIDS“ Generally, it is the total level of a hormone that is measured. Many factors can alter…
