ANATOMIC LOCALIZATION
ANATOMIC LOCALIZATION Part of “CHAPTER 75 – CUSHING SYNDROME“ DETECTION OF PITUITARY LESIONS After the diagnosis of Cushing disease has been established on clinical and biochemical grounds, the presence of…
CLINICAL PRESENTATIONS
CLINICAL PRESENTATIONS Part of “CHAPTER 75 – CUSHING SYNDROME“ The clinical manifestations of Cushing syndrome are determined by the increased abnormal secretion of cortisol, ACTH, and other adrenocortical steroids under…
CORTICOTROPIN-INDEPENDENT CUSHING SYNDROME
CORTICOTROPIN-INDEPENDENT CUSHING SYNDROME Part of “CHAPTER 75 – CUSHING SYNDROME“ Primary nodular hyperplasia, adrenocortical adenomas, and carcinomas as well as rare cases of ectopic cortisol production by tumor are found…
CORTICOTROPIN-DEPENDENT CUSHING SYNDROME
CORTICOTROPIN-DEPENDENT CUSHING SYNDROME Part of “CHAPTER 75 – CUSHING SYNDROME“ PITUITARY CORTICOTROPIN-DEPENDENT CUSHING SYNDROME Approximately 85% of patients with pituitary ACTH-dependent Cushing syndrome, also called Cushing disease, have pituitary microadenomas….
PATHOPHYSIOLOGY
PATHOPHYSIOLOGY Part of “CHAPTER 75 – CUSHING SYNDROME“ Cushing syndrome can be exogenous, resulting from the administration of glucocorticoids or ACTH, or endogenous, resulting from a primary increased secretion of…
CUSHING SYNDROME
CUSHING SYNDROME David E. Schteingart Cushing syndrome is the clinical expression of the metabolic effects of persistent, inappropriate hypercortisolism. Since the disorder was first described by Harvey Cushing in 1932,…
TESTS FOR LOCALIZATION
TESTS FOR LOCALIZATION Part of “CHAPTER 74 – TESTS OF ADRENOCORTICAL FUNCTION“ Four tests are useful in localizing the site of disease in disorders of adrenal function: petrosal sinus sampling,…
TESTS FOR CONGENITAL ADRENAL HYPERPLASIA
TESTS FOR CONGENITAL ADRENAL HYPERPLASIA Part of “CHAPTER 74 – TESTS OF ADRENOCORTICAL FUNCTION“ Related posts: STRUVITE STONES CORTICOTROPIN-DEPENDENT CUSHING SYNDROME ANGIOTENSIN RECEPTORS PRESYNAPTIC MODULATION CONTRASEXUAL PRECOCIOUS PUBERTY IDIOPATHIC OR…
TESTS FOR ADRENAL HYPOFUNCTION
TESTS FOR ADRENAL HYPOFUNCTION Part of “CHAPTER 74 – TESTS OF ADRENOCORTICAL FUNCTION“ The normal ranges of plasma cortisol and urinary free cortisol overlap the detection limit of most assays….
