ALDOSTERONE
ALDOSTERONE Part of “CHAPTER 79 – RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE“ Aldosterone is the most potent of several mineralocorticoid steroid hormones that act on the epithelium, especially in the kidney, to…
ACTIONS OF ANGIOTENSIN II
ACTIONS OF ANGIOTENSIN II Part of “CHAPTER 79 – RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE“ Renal Sodium and Water Retention. The best known function of A-II is to support the circulation under…
ANGIOTENSIN RECEPTORS
ANGIOTENSIN RECEPTORS Part of “CHAPTER 79 – RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE“ A-II binds and acts on its receptors at the cell surface. Several receptor subtypes have been found, including the…
TISSUE RENIN-ANGIOTENSIN SYSTEM
TISSUE RENIN-ANGIOTENSIN SYSTEM Part of “CHAPTER 79 – RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE“ Local renin-angiotensin systems in multiple tissues can produce A-II independently of the circulating renin-angiotensin system (Table 79-1). Their…
ANGIOTENSIN METABOLISM
ANGIOTENSIN METABOLISM Part of “CHAPTER 79 – RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE“ Of the several active angiotensins, A-II is the most important. The enzymes that are most active in degrading angiotensin…
ANGIOTENSIN I-CONVERTING ENZYME
ANGIOTENSIN I-CONVERTING ENZYME Part of “CHAPTER 79 – RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE“ Angiotensin I-converting enzyme (ACE) converts the inactive decapeptide angiotensin I to the active octapeptide angiotensin II (Fig. 79-4)….
THE RENIN-ANGIOTENSIN SYSTEM
THE RENIN-ANGIOTENSIN SYSTEM Part of “CHAPTER 79 – RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE“ ANGIOTENSINOGEN Angiotensinogen (AGT), also termed renin substrate, is the precursor for the angiotensin peptides, which include angiotensin (A)-I,…
RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE
RENIN-ANGIOTENSIN SYSTEM AND ALDOSTERONE Dalila B. Corry Michael L. Tuck THE RENIN-ANGIOTENSIN SYSTEM ANGIOTENSIN I-CONVERTING ENZYME Related posts: REGULATION OF THE GROWTH HORMONE RECEPTOR AND BINDING PROTEIN GONADOTROPE ADENOMAS OF…
MINERALOCORTICOIDS
MINERALOCORTICOIDS Part of “CHAPTER 78 – CORTICOSTEROID THERAPY“ PHARMACOLOGY Mineralocorticoids are 21-carbon steroids characterized by their effects on fluid and electrolyte balance. They promote renal sodium reabsorption and potassium excretion…
GLUCOCORTICOIDS
GLUCOCORTICOIDS Part of “CHAPTER 78 – CORTICOSTEROID THERAPY“ STRUCTURE OF COMMONLY USED GLUCOCORTICOIDS Figure 78-1 indicates the structures of several commonly used glucocorticoids.1,2 Cortisol (hydrocortisone) is the principal circulating glucocorticoid…
