Condition Association Genetic abnormalities, including: Down syndrome Acute myeloblastic leukaemia Beckwith-Wiedemann Wilms tumour, hepatoblastoma Fanconi anaemia Acute myeloblastic leukaemia Immunodeficiency, including: All conditions (congenital and acquired) Lymphoma HIV Non-Hodgkin’s lymphoma,…
Fig. 21.1 Distribution of primary sites of rhabdomyosarcoma and survival according to tumor location Different tumor sites may be associated to different RMS subtype: botryoid histology is seen commonly in…
Fig. 26.1 Suggested diagnostic work-up for staging of Kaposi sarcoma It is now known that the pathogenesis of all clinical variants of KS involves infection with KSHV, a deoxyribonucleic acid…
Allogeneic donor type Source HLA matching and cell dose Sibling Peripheral blood Match sibling donor: 6/6, 8/8 or 10/10 Mismatch sibling donor: over 8/10 Bone marrow Haploidentical: less than 9/10…
Diagnosis Location Standard treatment Options Outcome in high-income countries Prognostic factors Low-grade glioma in surgical areas All sites Surgery None Excellent (95–100 % survival) Extent of resection Unresectable low-grade glioma…
Common gram-positive pathogens Coagulase-negative staphylococci Staphylococcus aureus, including methicillin-resistant strains Enterococcus species, including vancomycin-resistant strains Viridans group streptococci Streptococcus pneumoniae Streptococcus pyogenes Common gram-negative pathogens Escherichia coli Klebsiella spp. Enterobacter…
Cancer cachexia Multifactorial • Disease • Host • Socio-economic • Treatment Interactive tumour and host-related effects • Socio-economic, inadequate supply of nutrients • Anorexia • Bowel obstruction • Malabsorption •…
Antineoplastics Section Antimicrobials Section Supportive care agents Section Asparaginase 8.2 Acyclovir 6.4.1 Allopurinol 8.2 Bleomycin 8.2 Amikacin 6.2.4 Amitriptyline 24.2.1 Carboplatin 8.2 Amphotericin B 6.3 Codeine 2.2 Cisplatin 8.2 Cefotaxime…
Fig. 20.1 Clinical presentation of retinoblastoma (a) leukocoria (b) massive orbital dissemination Biology and Patterns of Spread Regardless of the specific mutation, the tumor grows from the nuclear layer of…
Incidence of NHL per million person-years Males Females Age (years) <5 5–9 10–14 15–19 <5 5–9 10–14 15–19 Burkitt 3.2 6 6.1 2.8 0.8 1.1 0.8 1.2 Lymphoblastic 1.6…
