Early Warning Signs of Cancer in Children/Models for Early Diagnosis

Sep 20, 2016 by in HEMATOLOGY Comments Off on Early Warning Signs of Cancer in Children/Models for Early Diagnosis

Condition Association Genetic abnormalities, including:  Down syndrome Acute myeloblastic leukaemia Beckwith-Wiedemann Wilms tumour, hepatoblastoma Fanconi anaemia Acute myeloblastic leukaemia Immunodeficiency, including:  All conditions (congenital and acquired) Lymphoma HIV Non-Hodgkin’s lymphoma,…

read more

Soft Tissue Sarcomas

Sep 20, 2016 by in HEMATOLOGY Comments Off on Soft Tissue Sarcomas

Fig. 21.1 Distribution of primary sites of rhabdomyosarcoma and survival according to tumor location Different tumor sites may be associated to different RMS subtype: botryoid histology is seen commonly in…

read more

HIV and Malignancy in Children

Sep 20, 2016 by in HEMATOLOGY Comments Off on HIV and Malignancy in Children

Fig. 26.1 Suggested diagnostic work-up for staging of Kaposi sarcoma It is now known that the pathogenesis of all clinical variants of KS involves infection with KSHV, a deoxyribonucleic acid…

read more

Hematopoietic Stem Cell Transplant

Sep 20, 2016 by in HEMATOLOGY Comments Off on Hematopoietic Stem Cell Transplant

Allogeneic donor type Source HLA matching and cell dose Sibling Peripheral blood Match sibling donor: 6/6, 8/8 or 10/10 Mismatch sibling donor: over 8/10 Bone marrow Haploidentical: less than 9/10…

read more

Paediatric Neuro-Oncology

Sep 20, 2016 by in HEMATOLOGY Comments Off on Paediatric Neuro-Oncology

Diagnosis Location Standard treatment Options Outcome in high-income countries Prognostic factors Low-grade glioma in surgical areas All sites Surgery None Excellent (95–100 % survival) Extent of resection Unresectable low-grade glioma…

read more

Care and Prevention of Infection

Sep 20, 2016 by in HEMATOLOGY Comments Off on Care and Prevention of Infection

Common gram-positive pathogens Coagulase-negative staphylococci Staphylococcus aureus, including methicillin-resistant strains Enterococcus species, including vancomycin-resistant strains Viridans group streptococci Streptococcus pneumoniae Streptococcus pyogenes Common gram-negative pathogens Escherichia coli Klebsiella spp. Enterobacter…

read more

Nutritional Assessment and Intervention

Sep 20, 2016 by in HEMATOLOGY Comments Off on Nutritional Assessment and Intervention

Cancer cachexia Multifactorial • Disease • Host • Socio-economic • Treatment Interactive tumour and host-related effects • Socio-economic, inadequate supply of nutrients • Anorexia • Bowel obstruction • Malabsorption •…

read more

Essential Medicines and Pharmacy Services

Sep 20, 2016 by in HEMATOLOGY Comments Off on Essential Medicines and Pharmacy Services

Antineoplastics Section Antimicrobials Section Supportive care agents Section Asparaginase 8.2 Acyclovir 6.4.1 Allopurinol 8.2 Bleomycin 8.2 Amikacin 6.2.4 Amitriptyline 24.2.1 Carboplatin 8.2 Amphotericin B 6.3 Codeine 2.2 Cisplatin 8.2 Cefotaxime…

read more

Retinoblastoma

Sep 20, 2016 by in HEMATOLOGY Comments Off on Retinoblastoma

Fig. 20.1 Clinical presentation of retinoblastoma (a) leukocoria (b) massive orbital dissemination Biology and Patterns of Spread Regardless of the specific mutation, the tumor grows from the nuclear layer of…

read more

Non-Hodgkin Lymphoma

Sep 20, 2016 by in HEMATOLOGY Comments Off on Non-Hodgkin Lymphoma

  Incidence of NHL per million person-years  Males Females Age (years) <5 5–9 10–14 15–19 <5 5–9 10–14 15–19 Burkitt 3.2 6 6.1 2.8 0.8 1.1 0.8 1.2 Lymphoblastic 1.6…

read more
Get Clinical Tree app for offline access