Luminal A Luminal B Basal-like or TNCB HER2/ErbB2 Normal-like Claudin-low Genetic signature Luminal A (estrogen receptor positive and/or progesterone receptor positive, HER2 negative) Luminal B (estrogen receptor positive and/or…
BRCA 1 CD105 BRCA 2 Survivin HER2 gene (HER2/neu or ErbB2) COX-2 MYC Ki67 ER Tropomyosins PR NAT1 BRST2 RAD51B (14q24.1) AR TOX3 (16q12.1) C-erb-2 rs13387042 (2q35) p53 rs10941679 (5p12)…
Chemical shift Multiplicity Assignment p-value (pCR vs. SD) p-value (pCR vs. PR) p-value (PR vs. SD) 4.24 m Threonine 0.04 0.28 0.30 1.00 s Isoleucine 0.04 0.01 0.02 2.09 m…
Gene ID Symbol Function of gene 2064 ERBB2/HER2 Epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification and/or overexpression has been reported in numerous cancers 7153 TOP2A DNA…
Fig. 1.1 Relationship between gene, DNA, RNA, and protein (the central dogma of molecular biology) with omics technologies Genomics Genomics may be described as the comprehensive analysis of genes and…
Fig. 6.1 Bioactive food components and its integration with various molecular streams in phenotype progression and development Table 6.1 Factors affecting nutrigenomic research and phenotype Approach Definition and factors Transcriptomics…
Gene (description) Function Sample obtained Case # Methy. status Marker Reference 14-3-3-σ/stratifin (SFN) Cell cycle regulation Cell lines, tissue 20 Hyper Therapeutic Ferguson et al. [202] 14-3-3-σ/stratifin (SFN)å Cell cycle…
