Heavy-Chain Disease

Jun 6, 2017 by in ONCOLOGY Comments Off on Heavy-Chain Disease

Feature Type of heavy-chain disease α γ μ Year described 1968 1964 1969 Incidence Rare Very rare Very rare Age at diagnosis Young adult (<30 years) Older adult (60–70 years)…

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Pathology of Non-Hodgkin’s and Hodgkin’s Lymphomas

Jun 6, 2017 by in ONCOLOGY Comments Off on Pathology of Non-Hodgkin’s and Hodgkin’s Lymphomas

Low grade A. Malignant lymphoma, small lymphocytic Consistent with chronic lymphocytic leukemia Plasmacytoid B. Malignant lymphoma, follicular, predominantly small cleaved cell Diffuse areas Sclerosis C. Malignant lymphoma, follicular, mixed small…

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Pathology of the Chronic Myeloid Leukemias

Jun 6, 2017 by in ONCOLOGY Comments Off on Pathology of the Chronic Myeloid Leukemias

Fig. 3.1 Peripheral blood (PB) film from a patient with chronic myelogenous leukemia with an unusually high white cell count showing an increase of neutrophils, eosinophils, basophils, and granulocyte precursors….

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The Etiology of Acute Leukemia

Jun 6, 2017 by in ONCOLOGY Comments Off on The Etiology of Acute Leukemia

Fig. 14.1 The two-hit model of acute leukemogenesis. This model hypothesizes that AML and ALL are the consequence of a combination of at least two broad classes of mutations. Class…

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Psychological Aspects of Hematological Neoplasms

Jun 6, 2017 by in ONCOLOGY Comments Off on Psychological Aspects of Hematological Neoplasms

Cognitive Evaluation of the danger versus one’s coping resources. Focus is on the perceived threat while extraneous detail environmental details are blocked out (tunnel vision). For example, a patient may…

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Immunobiology of Acute Leukemia

Jun 6, 2017 by in ONCOLOGY Comments Off on Immunobiology of Acute Leukemia

Earliest definition Current definition ECOG’s new definition Myeloid Myeloid Myeloid HLA-DR NEG HLA-DR NEG HLA-DRNEG CD34 HLA CD34 NEG CD11a NEG CD15 NEG CD18NEG CH15s POS CD133 NEG CD9 POS…

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