Ultrasound CT MRI Advantages Low cost Low cost No radiation Availability Availability High contrast resolution Useful for screening and surveillance Quick Liver-specific agents High spatial resolution Functional MRI Highest…
Fig. 1 IL-6/STAT3 signaling pathway. Shown is a schematic figure of the IL-6/JAK/STAT signaling pathway. Binding of IL-6 to its cognate receptor results in phosphorylation of JAK1/2 with subsequent autophosphorylation of…
Tumor classification Definition Stage Criteria T0, N0, M0 Not found Stage I T1 T1 One nodule <2.0 cm Stage II T2 T2 One nodule 2.0–5.0 cm; 2 or 3 nodules, all <3.0 cm Stage III T3 T3…
Without underlying liver disease With underlying liver disease p value Number 82 124 − Liver disease, n (%) HBV (HBsAg+) HCV (anti-HCV Ab+) NASH Alcoholic liver disease Other −…
Fig. 1 Algorithm for management of transplantable hepatocellular carcinoma at Henri Mondor Hospital, Creteil, France [3] For patients with a solitary HCC<5 cm, no evidence of extrahepatic tumor burden, compensated liver disease,…
Classification Stages/Scores Parameters Survival/Stage (%) Hepatitis (%) Study area of origin Tumor characteristics Liver function Health status Hepatitis B Hepatitis C Both Okuda I, II, III </>50 % liver involvement Bilirubin,…
Characteristic TheraSphere® SIR-Sphere® Isotope 90Y 90Y Half-Life (h) 64.2 64.2 Particle Size (μm) 20–30 20–60 Range of spheres per vial 1.2–8.0 million 40–80 million Activity per sphere (Bq) 2500 50…
Stage AJCC- clinical staging AJCC-staging I 81 (51 %) 60 (38 %) II 57 (36 %) 49 (31 %) III 7 (4 %) 9 (6 %) IV 0 1 (0.6 %) No lesions 14 (9 %) 12 (7 %)…
Fig. 1 Treatment algorithm of patients with HCC based on serum bilirubin level and indocyanine green retention rate at 15 min. Adapted from Makuuchi et al. [8] 2.3 Assessment of the Future…
Chemical ablation – Ethanol injection Thermal ablation – Radiofrequency ablation – Microwave ablation – Laser ablation – Cryoablation Irreversible electroporation 2 Chemical Ablation The seminal…
