Oncohema Key

Fig. 10.1 Estimated age-standardized rates (world) per 100,000 incidence and mortality of cancer in more and less developed countries (GLOBOCAN 2012) 10.2 Indian Scenario With an estimated burden of over…

Fig. 23.1 Inhibition of tumorsphere formation by CQ Conclusions Since small subpopulations of CSCs were identified from blood mononuclear cells in human acute myeloid leukemia in 1997, it has attracted…

Fig. 7.1 Overexpression of TG2 (left panel) in epithelial cells (shown are MCF10A mammary epithelial cells) is associated with their transdifferentiation into mesenchymal looking cells (EMT; a), increased invasion (through…

Fig. 4.1 Illustration of microenvironmental factors involved in CLL survival 4.3 Role of Apoptosis Pathway Members in CLL Pathophysiology Based on their structure and/or functional homology, major protein groups of…

Fig. 16.1 Schematic representation of the mitochondrial respiratory chain The concept of ‘aerobic glycolysis’ suggested by Warburg implies that cancer cells predominantly depend on glycolysis for energy production and to…

Edwin Smith Papyrus (3000 BC) Described a breast cancer-like disease Eberus Papyrus (1500 BC) Described soft tissue tumors and used cautery, knives, salts, and arsenic paste to treat this Hippocrates…

Fig. 6.1 Schematic representation of OPN structure and its receptors. OPN contains binding sites for different integrins at N-terminus and CD44 receptors at C-terminus. It also encompasses calcium-binding site and…