Biomarkers for Determining the Prognosis of CML
Reference N Response C0 (ng/mL) P value N ≤1000 N >1000 Marin et al. [10] 84 CMR 43 23.3 % 41 44.4 % 0.14 MMR 60.1 % 83.2 % 0.02 Takahashi et al. [41]…
Identification and Biology of CML Stem Cells
Fig. 1.1 Clonal expansion of CML hematopoiesis. A reciprocal translocation between chromosomes 9 and 22 occurs at a hematopoietic stem cell (HSC) stage. This pre-leukemic stem cell expresses BCR-ABL at…
