World Health Organization classification for myeloproliferative neoplasms 2008 Chronic myelogenous leukemia Polycythemia vera Essential thrombocythemia Primary myelofibrosis Chronic neutrophilic leukemia Chronic eosinophilic leukemia, not otherwise specified Hypereosinophilic syndrome Mast cell…
In a series of 400 patients older than 70 with cancer, Luciani et al. [37] studied the SOF (Study of Osteoporotic Fractures) index versus geriatric assessment including 7 questionnaires. Geriatric…
Signs and symptoms Nursing management Anaemia Palpitations Red blood cell transfusions Chest pain Administration of erythropoietin agents Fatigue Dyspnea Dizziness Headaches Neutropenia Fever Timely recognition of infection Cough Administration…
Year Author Number Median age Treatment Outcome Therapy associated death rate Comment 1994 Levis et al. [27] 65 72 years ABVD; MOPP/ABVD CR 67 % 8 year OS 46 %…
with indication of high risk by a score >87 and low risk by a score ≤87. Indirectly, the analysis proved that advanced age did not represent an adverse prognostic factor…
(a) Diffuse large B-cell lymphoma (DLBCL), NOS T-cell/histiocyte rich large B-cell lymphoma (T/HRBCL) EBV + DLBCL of the “elderly” (b) DLBCL with a predominant extranodal location Primary mediastinal (thymic) large B cell…
Small lymphocytic lymphoma/ chronic lymphocytic leukemia B-cell prolymphocytic leukemia Splenic marginal zone lymphoma Hairy cell leukemia Splenic B–cell lymphoma/leukemia unclassifiable a Splenic red pulp small B–cell lymphoma a Hairy cell…
Adverse event Novel agent Action Dose-reductions Neutropenia Lenalidomide, Bortezomib G-CSF until neutrophil recovery in case of uncomplicated grade 4 or grade 2–3 complicated by fever or infection. 25–50 % drug…
Fig. 7.1 Age-distribution among patients with newly diagnosed CLL Biology and Aging The etiology of CLL is unknown and its pathogenesis is not fully understood [2]. The reason why CLL…
