Differentiated Thyroid Cancer: Prognostic and Risk Assessment Systems
Year Diseasea Study size Age Size Extent/T-stage Lymphnode status Metastases Gender Grade Histology Others No. of riskgroups EORTC 1979 PTC, FTC,MTC, ATC 507 X X X X X 5…
The Debate against Elective Lymph Node Dissection in Papillary Thyroid Carcinoma
Arguments for elective neck surgery Arguments against elective neck surgery Improved staging Extremely low rates of recurrence if observed Improved targeting of adjuvant therapy Excellent survival without elective surgery Reduced…
Molecular Genetics of Thyroid Cancer
Tumor Genes Frequency Citations PTC BRAF 40–50% [2, 4–8] RET/PTC 10–20% [2, 9, 10] RAS 10–20% [11–15] TRK 5–13% [16] TERT 9% [2] EIF1AX 2% [2] FTC RAS 20–50% [13,…
Clinical Presentation and Diagnosis of Papillary Thyroid Cancer
© The Author(s) 2017Anne T. Mancino and Lawrence T. Kim (eds.)Management of Differentiated Thyroid Cancer10.1007/978-3-319-54493-9_6 6. Clinical Presentation and Diagnosis of Papillary Thyroid Cancer Cord Sturgeon1 , Dina Elaraj1 and Anthony Yang1 (1) Department of Surgery, Section of Endocrine…
Evaluation of a Thyroid Nodule
Sensitivity Specificity Ultrasound [29] 63–87 80–94% Elastography [30, 31] 92% 90% MRI [27] 90% 95% CT/PET [28, 32] 88–92% 64–87% In terms of correlation between physical exam findings and…
