Differential diagnosis PTH excess Malignancy Non-PTH endocrine causes Granulomatous disease Medications Miscellaneous PHPT Parathyroid adenoma Parathyroid carcinoma Multiglandular hyperplasia as part of MEN syndromes (MEN1 and 2A) FIH HPT-JT HHM…
© Mayo Foundation for Medical Education and Research 2016Ann E. Kearns and Robert A. Wermers (eds.)Hyperparathyroidism10.1007/978-3-319-25880-5_15 15. Primary Hyperparathyroidism in Pregnancy Haleigh James1 , Geoffrey B. Thompson2 and Robert A. Wermers1 (1) Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of…
© Mayo Foundation for Medical Education and Research 2016Ann E. Kearns and Robert A. Wermers (eds.)Hyperparathyroidism10.1007/978-3-319-25880-5_13 13. Medical Management of Primary Hyperparathyroidism Ann E. Kearns1 (1) Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Internal Medicine,…
Sporadic primary hyperparathyroidism Familial primary hyperparathyroidism Adenoma (85 %) Isolated Hyperplasia (15 %) MEN1 Carcinoma (<1 %) MEN2A MEN4 Hyperparathyroidism-jaw tumor Familial hypocalciuric hypercalcemia Tertiary hyperparathyroidism Autoimmune hypocalciuric hypercalcemia Chronic…
Fig. 10.1 Sonogram of the right side of the neck, sagittal view. (a) A mass (PC) measuring approximately 3.5 × 2.6 × 2.9 cm is seen lying along the inferior and posterior aspect of…
Assessment Serum calcium (> upper limit of normal) 1.0 mg/dL (0.25 mmol/L) Skeletal Bone mineral density: T-score ≤2.5 at lumbar spine, total hip, femoral neck, or distal 1/3 radius Vertebral…
© Mayo Foundation for Medical Education and Research 2016Ann E. Kearns and Robert A. Wermers (eds.)Hyperparathyroidism10.1007/978-3-319-25880-5_3 3. Nephrolithiasis in Primary Hyperparathyroidism Johann P. Ingimarsson1 and John C. Lieske2 (1) Department of Urology, Mayo College of Medicine, Mayo Clinic, Rochester,…
Fig. 7.1 4D computed tomography (CT) parathyroid scan demonstrating a 7-mm nodule with mild early arterial enhancement in the upper mediastinum, anterior to the aortic arch and to the right…
Fig. 5.1 Two-site immunoassay with bridging of two antibodies with antigen (left) and heterophile antibodies bridging the two antibodies (right) independent of the antigen, resulting in an increase in the…
Fig. 6.1 Parathyroid lipoadenoma with proliferation of parenchymal parathyroid tissue and stromal elements with adipose tissue comprising greater than 50 % of the adenoma. The parenchymal tissue is comprised of…
