Head and Neck Squamous Cell Carcinomas

Jun 25, 2017 by in ONCOLOGY Comments Off on Head and Neck Squamous Cell Carcinomas

“Classical-type” variants Verrucous carcinoma Basaloid squamous cell carcinoma Spindle cell (sarcomatoid) squamous cell carcinoma Papillary squamous cell carcinoma Adenosquamous carcinoma Lymphoepitheliomatous carcinoma Sinonasal non-keratinizing carcinoma Adenoid squamous (acantholytic) carcinoma HPV-associated…

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Factors for Oral Infection with Human Papillomavirus

Jun 25, 2017 by in ONCOLOGY Comments Off on Factors for Oral Infection with Human Papillomavirus

Fig. 1 Age-adjusted incidence by calendar year of diagnosis for human papillomavirus (HPV)-related sites (including base of tongue, lingual tonsil, tonsil, oropharynx, and Waldeyer ring) and HPV-unrelated sites (including other and…

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in HPV-Positive Tumors—The New Standard?

Jun 25, 2017 by in ONCOLOGY Comments Off on in HPV-Positive Tumors—The New Standard?

Fig. 1 Da Vinci Si® system Fig. 2 3D HD endoscope camera Fig. 3 Three-dimensional movement capacity With the Flex® Robotic System—developed specifically for transoral head and neck resections—the surgeon is able to…

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Staging and HPV-Related Oropharyngeal Cancer

Jun 25, 2017 by in ONCOLOGY Comments Off on Staging and HPV-Related Oropharyngeal Cancer

Primary tumor (T) TX Primary tumor cannot be assessed T0 No evidence of primary tumor Tis Carcinoma in situ T1 Tumor = 2 cm in greatest dimension T2 Tumor > 2 cm but not more than…

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Testing of Head and Neck Cancer in Clinical Practice

Jun 25, 2017 by in ONCOLOGY Comments Off on Testing of Head and Neck Cancer in Clinical Practice

Fig. 1 VU University Medical Centre HPV test algorithm 3.2 The Johns Hopkins Medical Institutions HPV Test Algorithm This algorithm (Fig. 2) was developed by The Johns Hopkins Medical Institutions, USA (Singhi…

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Patterns and Biology of HPV-Associated HNSCC

Jun 25, 2017 by in ONCOLOGY Comments Off on Patterns and Biology of HPV-Associated HNSCC

First author Year Anatomical site HPV- HPV+ Differently expressed genes (probes) Analyzed genes (probes) Oropharynx Oral cavity Tonsils Base of tongue/tongue Larynx Hypopharynx Keck 2014 X X   X  75 55…

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Expectations in HNSCC

Jun 25, 2017 by in ONCOLOGY Comments Off on Expectations in HNSCC

  Cervarix Gardasil Gardasil 9 HPV coverage 16, 18 6, 11, 16, 18 6, 11, 16, 18, 31, 33, 45, 52, 58 Manufacturer GlaxoSmithKline Merck Merck Producing cells Trichoplusia ni…

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