Overview of Venous Thromboembolism
Overview of Venous Thromboembolism Sam Schulman Victor J. Marder Gilbert C. White II HISTORICAL BACKGROUND Thrombosis as a clinical condition was probably described almost 5,000 years ago, when the Chinese…
New Approaches for the Therapy of Bleeding Disorders, Including Gene Therapy
New Approaches for the Therapy of Bleeding Disorders, Including Gene Therapy Gilbert C. White II Harold R. Roberts Better understanding of the molecular mechanisms of blood coagulation and the structure…
Platelets, Plasma, and Specialized Coagulation Concentrate Therapies
Platelets, Plasma, and Specialized Coagulation Concentrate Therapies Thomas S. Kickler The biggest driving force in improving the safety of transfusion therapy in bleeding disorders has been the concern by patients…
Therapy with Antifibrinolytic Agents
Therapy with Antifibrinolytic Agents Daphne B. Stewart Victor J. Marder After hemostasis is established in an injured vessel, a highly orchestrated process follows to heal the vessel and to reestablish…
Management of Acute Hemorrhage
Management of Acute Hemorrhage Micah J. Mooberry Rommel P. Lu Nigel S. Key Evaluation and management of the acutely bleeding patient is a common encounter for the hematologist and is…
Overview of Therapy of Bleeding Disorders
Overview of Therapy of Bleeding Disorders Gilbert C. White II Sam Schulman Victor J. Marder Historically, once it was recognized that blood clotting factors were components of plasma, the notion…
Retinopathy
Retinopathy Jing Chen Andreas Stahl Lois E. H. Smith The eye is one of the most important sensory organs that enables us to perceive the environment to ensure species survival….
Intracranial Hemorrhage and Subarachnoid Hemorrhage
Intracranial Hemorrhage and Subarachnoid Hemorrhage Timolaos Rizos Thorsten Steiner INTRACEREBRAL HEMORRHAGE Epidemiology, Risk Factors and Prognosis Intracerebral hemorrhage (ICH) is an extravasation of blood into the brain parenchyma. Hemorrhagic stroke…
Aneurysms (Large and Small Arteries)
Aneurysms (Large and Small Arteries) Carlos E. Sanchez Sangita Kapur Neal L. Weintraub Aneurysms of the aorta and its branch vessels are a major health care concern; more than 15,000…
Arteriovenous Malformations and Hemangiomas and Cerebral Cavernous Malformations
Arteriovenous Malformations and Hemangiomas and Cerebral Cavernous Malformations Kevin J. Whitehead Douglas A. Marchuk Mark L. Kahn The cardiovascular system is organized into a hierarchical, branching arrangement by which blood…
