Factor V and Factor VIII
Factor V and Factor VIII Randal J. Kaufman Philip J. Fay Laura Popolo Thomas L. Ortel Factor V and factor VIII are two homologous nonenzymatic proteins that play a critical…
Tissue Factor and the Initiation and Regulation (TFPI) of Coagulation
Tissue Factor and the Initiation and Regulation (TFPI) of Coagulation James H. Morrissey George J. Broze Jr. Blood circulates as a liquid, but once it escapes from an injured blood…
Genetics of Coagulation
Genetics of Coagulation Rodney M. Camire Paris Margaritis The determination of the gene, complementary deoxyribonucleic acid (cDNA), and amino acid sequences of all of the proteins known to be involved…
The Blood Coagulation Factors and Inhibitors: Their Primary Structure, Complementary DNAs, Genes, and Expression
The Blood Coagulation Factors and Inhibitors: Their Primary Structure, Complementary DNAs, Genes, and Expression Dominic W. Chung Wenfeng Xu Earl W. Davie A BRIEF INTRODUCTION TO THE BLOOD COAGULATION CASCADE…
Overview of Basic Coagulation and Fibrinolysis
Overview of Basic Coagulation and Fibrinolysis Gilbert C.White II Victor J. Marder Sam Schulman William C. Aird Joel S. Bennett The development of a fibrin clot occurs after a series…
Biostatistics and Epidemiology: The Basic Science of Clinical Research
Biostatistics and Epidemiology: The Basic Science of Clinical Research Kerry L. Lee In the basic sciences, there is an essential knowledge base and an array of tools and techniques that…
Overview of the Immune System
Overview of the Immune System Andrew H. Lichtman The immune system is a complex collection of molecules, cells, tissues, and organs whose major function is to protect hosts from microbial…
Cell Biology, Protein Processing, and Cell Signaling
Cell Biology, Protein Processing, and Cell Signaling Randal J. Kaufman Laura Popolo In order to perform their multiple functions, eukaryotic cells have evolved an internal structural organization that consists of…
Coagulation Enzymology
Coagulation Enzymology Sriram Krishnaswamy THE CONTEXT Blood coagulation is initiated by the exposure of tissue factor to flowing blood following vascular damage.1,2 A series of highly specific proteolytic activation steps…
Molecular and Clinical Genetics
Molecular and Clinical Genetics Lesley Everett Karl Desch David Ginsburg Keeping up to date with the remarkable progress in human genetics and the rapidly changing genomic laboratory toolbox poses a…
