Familial Pancreatic Adenocarcinoma
Familial pancreatic cancer (FPC) kindreds have at least 2 first-degree relatives with pancreatic ductal adenocarcinoma. Studies of FPC have focused on the discovery of genetic cause and on the management…
Mouse Models of Pancreatic Ductal Adenocarcinoma
Only 10% to 15% of patients with pancreatic ductal adenocarcinoma (PDAC) are candidates for potentially curative surgery due to the location or spread of disease at the time of diagnosis….
Genetics and Biology of Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma remains a clinical challenge. Thus far, enlightenment on the downstream activities of Kras, the tumor’s unique metabolic needs, and how the stroma and immune system affect it…
Pancreatic Cancer
Brian M. Wolpin, MD, MPH, Editor Although pancreatic cancer remains a leading cause of cancer death, steady progress is being made in understanding the biology of the disease and optimal…
