Radiation Therapy in Gynecologic Cancer
Fig. 7.1. Axial CT view of an image-guided IMRT plan for cervical cancer. Image courtesy of C. Yashar. Fig. 7.2. Coronal CT view of an image-guided IMRT plan for vulvar…
Fig. 7.1. Axial CT view of an image-guided IMRT plan for cervical cancer. Image courtesy of C. Yashar. Fig. 7.2. Coronal CT view of an image-guided IMRT plan for vulvar…
Fig. 8.1. Airway pressure curve at the end of inspiration and held expiration. Initial decrease in peak pressure followed by the plateau pressure. An acute change in upper airway resistance…
Fig. 5.1. (a) Complete hydatidiform mole. All chorionic villi are enlarged and have abnormal shapes. There is marked hyperplasia of the trophoblast. Circumferential proliferation of the trophoblast around the villi…
Opioid Dosage form Strength Starting doses of short-acting opioids for opioid naïve patients Morphine Oral solution Tablets ER (q12 h) Tablets ER (q 24 h) Tablets IR Injectable SC, IV,…
Fig. 3.1. Histolopathologic Types of Carcinoma of the Vulva: SEER Data 1988–2001 [2]. Data source: Kosary CL. Cancer of the Vulva. In: Ries LAG, Young JL, Keel GE, Eisner MP,…
Risk factor Nulliparity Early menarche Late menopause Increasing age White race Family history Personal history of breast cancer Hormone replacement therapya Fertility drugsa Talca aControversial Early Detection and Screening for…
E1 E2 E4 E5 E6 E7 L1 L2 ATPase Regulator of E6 and E7 Disrupts cytokeratin matrix for release of virions Potentiation of membrane bound EGF receptors Bind and inactivate…
Panici trial ASTEC trial #Patients 514 1408 Eligibility Clinical Stage I, >50 % myometrial invasion (excluded Stage IB grade 1), age <75, good performance status, no prior RT or…
Agent Mechanism of action Toxicities Clinical pearls Paclitaxel [1, 2] Antimicrotuble agent; stabilizes microtubules inhibiting interphase and mitosis •Myelosuppression •Nausea/vomiting (low risk) •Peripheral neuropathy •Arthralgia/myalgia •Hypersensitivity •Alopecia •Vascular irritant •Should…