Neuroblastoma

Sep 1, 2019 by in ENDOCRINOLOGY Comments Off on Neuroblastoma

Fig. 9.1 Symptomless neck mass Fig. 9.2 Incidental finding on chest X-ray The abdomen accounts for 60% of the primary tumours half of these arise in the suprarenal gland. A further 15%…

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Paediatric and Adolescent Breast Disorders

Sep 1, 2019 by in ENDOCRINOLOGY Comments Off on Paediatric and Adolescent Breast Disorders

Stage Characteristics 1 Pre-adolescent: Elevation of breast papilla/nipple 2 Breast bud stage: Elevation of the breast and papilla as small mound and enlargement of areola 3 Further enlargement of breast…

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Pancreas Embryology, Anatomy, and Physiology

Sep 1, 2019 by in ENDOCRINOLOGY Comments Off on Pancreas Embryology, Anatomy, and Physiology

Fig. 11.1 Cell lineage schematic for pancreatic development from a multipotent progenitor stem cell Basic Anatomy The human pancreas is a long tapered glandular organ, which lies in the retroperitoneum. It…

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Testis Embryology, Anatomy and Physiology

Sep 1, 2019 by in ENDOCRINOLOGY Comments Off on Testis Embryology, Anatomy and Physiology

Fig. 19.1 The two stages of testicular descent. Between 8 and 15 weeks the gubernaculum or genito-inguinal ligament enlarges in male embryos under the action of Insl3 [augmented by MIS/AMH (?)]. This…

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Congenital Hyperinsulinism

Sep 1, 2019 by in ENDOCRINOLOGY Comments Off on Congenital Hyperinsulinism

Drug Dose Route of administration Side effects Diazoxide 5–20 mg/kg/day divided into three doses Oral Fluid retention, hypertrichosis Chlorothiazide (in conjunction with diazoxide) 7–10 mg/kg/day divided into two doses Oral Hyponatraemia, hypokalaemia…

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