Management of Isolated Liver Metastases Rebecca Miksad Douglas W. Hanto Robert D. Timmerman Steven Come INTRODUCTION About half of patients with metastatic breast cancer develop liver metastases, a finding that…
Ophthalmic Metastases Christopher A. Barker Beryl McCormick David H. Abramson Ophthalmic metastases refer to secondary malignant neoplasms occurring in or around the eye. The uvea is the highly vascular middle…
Brachial Plexopathy in Patients with Breast Cancer Nathan I. Cherny Pauline T. Truong The brachial plexus is a somatic nerve plexus formed by intercommunications among the ventral rami of the…
Leptomeningeal Metastasis Eli L. Diamond Lisa M. DeAngelis Leptomeningeal metastasis (LM) occurs when tumor spreads to the subarachnoid space and cerebrospinal fluid (CSF) that surround the brain and spinal cord….
Metastatic Epidural Spinal Cord Compression Soma Sengupta Michael W. Groff Nils D. Arvold Patrick Y. Wen INTRODUCTION Epidural spinal cord compression (ESCC), resulting from tumor growth in the spinal epidural…
Brain Metastases Nancy U. Lin Brian M. Alexander Ian F. Dunn The management of patients with brain metastases from breast cancer remains a challenging clinical problem. The goals of treatment…
Newer Targeted Therapy Ingrid A. Mayer Carlos L. Arteaga Advances in tumor genetics and drug development over the last decade have led to the generation of a wealth of anti-cancer…
Management Summary for the Care of Patients with Metastatic Breast Cancer Marc E. Lippman Very unfortunately, metastatic breast cancer remains largely incurable. Therefore, the primary goals of therapy are the…
Palliative Care in Breast Cancer M. Jennifer Cheng Thomas J. Smith INTRODUCTION Breast cancer is still the most common cancer in women and nearly half of those diagnosed will die…
Treatment of HER2-overexpressing Metastatic Breast Cancer Shruti Sheth Sumanta Kumar Pal Mark D. Pegram INTRODUCTION In 2013, it is estimated that 232,340 new cases of breast cancer will be diagnosed…
