Towards an Intermediate Grade in Glioma Classification
Fig. 5.1 Three examples (a = case 1; b = case 2; c = case 3) of microfoci of “intermediate grade” at low magnification (left) and at high magnification (right)…
The Genomics of Diffuse Low-Grade Gliomas
Molecular markers Prevalence (n > 1000 glioma subjects) (%) IDH mutation only 45 Triple-positive [TERTp-mut, IDH-mut, 1p/19q codeletion] 29 TERTp-mutation only 10 Triple negative [TERTp- wild type, IDH-wild type, 1p/19q…
Dissemination of Diffuse Low-Grade Gliomas: Tools and Molecular Insights
Fig. 7.1 (a) Photograph of a grade II diffuse glioma culture maintained 2 weeks after resection. (b) Detection of cells expressing the mutated form of IDH1 with R132H specific antibody….
Pathogenesis of Diffuse Low-Grade Gliomas
Type-1 Type-2 Type-3a Type-3b Clinical characteristics Age, median (IQR), y 45 (36–54) 36 (30–44) 43 (28–49) 57 (46–64) OS, mean (95% CI), y 16.38 (14.15–NA) 7.88 (6.76–9.70) 9.13 (5.05–NA)…
Introduction: From the Inhibition of Dogmas to the Concept of Personalized Management in Patients with Diffuse Low-Grade Gliomas
© Springer-Verlag London Ltd. 2017Hugues Duffau (ed.)Diffuse Low-Grade Gliomas in Adults10.1007/978-3-319-55466-2_1 1. Introduction: From the Inhibition of Dogmas to the Concept of Personalized Management in Patients with Diffuse Low-Grade Gliomas Hugues Duffau1, 2 (1) Department…
