© Springer International Publishing Switzerland 2017Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai and Brian O’Sullivan (eds.)Critical Issues in Head and Neck Oncology10.1007/978-3-319-42909-0_19 19. Symptoms at End-of-Life of Head and Neck Cancer Patients Dirk Schrijvers1 (1)…
© Springer International Publishing Switzerland 2017Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai and Brian O’Sullivan (eds.)Critical Issues in Head and Neck Oncology10.1007/978-3-319-42909-0_18 18. Quality of Life Issues Susanne Singer1 (1) Division of Epidemiology and Health…
Mechanism Specification 1. Reduced antigen processing and presentation Downregulation or mutation of HLA class molecules 2. Tumour-permissive cytokine profile Increase of immunosuppressive cytokines: TGF-β, IL-6 Decrease of stimulatory cytokines: IL-2,…
Assessment of functioning Social assessment Definition: ability to live independently at home and in the community, physical performance (mobility, balance, fall risk) Definition: adequate social support to undergo treatment Measurement:…
© Springer International Publishing Switzerland 2017Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai and Brian O’Sullivan (eds.)Critical Issues in Head and Neck Oncology10.1007/978-3-319-42909-0_12 12. Salvage Surgery of Head and Neck Cancer C. René Leemans1 (1) VU University…
Setting Outcomes Janot et al. [19] GETTEC-GORTEC phase III trial (NCT00180934) n = 130 (65 each arm) Resectable recurrent HNC Sx + postoperative reRT (vs. Sx alone) Total 60…
Fig. 11.1 Acute toxicity relative risk values (T RR) and relative max-grade values for 13 head and neck treatment groups ranked by increasing relative risk. P platinum, H hydroxyurea, 5-FU…
© Springer International Publishing Switzerland 2017Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai and Brian O’Sullivan (eds.)Critical Issues in Head and Neck Oncology10.1007/978-3-319-42909-0_10 10. Treatment of Viral-Associated HNC (OPC and NPC) Shao Hui Huang1, Melvin L. K. Chua2, Francesca Caparrotti2 and…
Fig. 6.1 Expected emotions and reactions for the SCCHN patient Fig. 6.2 Recommended actions for the healthcare professional. DIC2 Distress Inventory for Cancer version 2, HADS Hospital Anxiety and Depression…
Fig. 4.1 Detection of high-risk HPV using RNAscope. Multiple nuclear dot-like signals are present in the neoplastic cells whilst the stromal cells are unlabeled Table 4.1 The performance of RNAscope…
