Health-Related Quality of Life

Jun 25, 2017 by in ONCOLOGY Comments Off on Health-Related Quality of Life

Fig. 30.1 Number of publications per year from January 1994 to December 2013 30.1.3 Patient-Reported Outcome Instruments HRQL is typically measured using Clinical Outcome Assessment (COA) tools, i.e., instruments designed…

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Palliative Care

Jun 25, 2017 by in ONCOLOGY Comments Off on Palliative Care

© Springer International Publishing 2017Archie Bleyer, Ronald Barr, Lynn Ries, Jeremy Whelan and Andrea Ferrari (eds.)Cancer in Adolescents and Young AdultsPediatric Oncology10.1007/978-3-319-33679-4_31 31. Palliative Care Karen Wasilewski-Masker1  , Tracy Howk2  , Erin Connelly2  , Sergey Postovsky3  , Pamela Brill2  , Kate Carlson Wrammert4   and Rathi Pillai4   (1) The Aflac Cancer &…

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Adolescent and Young Adult Cancer Survivors: Late Effects of Treatment

Jun 25, 2017 by in ONCOLOGY Comments Off on Adolescent and Young Adult Cancer Survivors: Late Effects of Treatment

Therapeutic exposure Potential late effect Vincristine, vinblastine Peripheral neuropathy, Raynaud’s phenomenon Corticosteroids Cataracts, osteopenia, osteoporosis, avascular necrosis Mercaptopurine Hepatic dysfunction, veno-occlusive disease Methotrexate (Systemic) osteopenia, osteoporosis, renal dysfunction, hepatic dysfunction…

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Fertility Preservation in the Pediatric Setting

Jun 25, 2017 by in ONCOLOGY Comments Off on Fertility Preservation in the Pediatric Setting

Agent Cumulative dose associated with azoospermia Cyclophosphamide >5–7.5 g/m2 associated with abnormal semen parameters, >19 g/m2 consistently result in azoospermia Ifosfamide >60 g/m2 Procarbazine >4 g/m2 Busulfan >600 mg/m2 Melphalan…

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