Immunopathology and Immunotherapy of Myeloid Leukemia
Fig. 5.1 Models of pathogenesis of AML. Three possible scenarios for the development of the LSC are shown. Hematopoietic stem cells (HSC) or myeloid progenitors (MP) or both populations are…
Immunotherapy for Pediatric Solid Tumors
62. Scursoni AM, Galluzzo L, Camarero S, Pozzo N, Gabri MR, de Acosta CM, et al. Detection and characterization of N-glycosylated gangliosides in Wilms tumor by immunohistochemistry. Pediatr Dev Pathol….
Immunotherapeutic Strategies for Multiple Myeloma
Mechanism Ag Short description of function Ab name Results of earlier trials Ongoing clinical trials mAbs targeting proteins involved in myeloma cell adhesion CS1 See text Elotuzumab Syndecan-1 (CD138) Cell…
Vaccination in Human Solid Tumors: Recent Progress in the Clinical Arena
1 Shared/self-/differentiation TAAs (e.g., Melan-A, PSA, CEA) 2 Shared/self-/cancer testis or germinal TAAs (e.g., MAGE, NY-ESO-1) 3 Universal TAAs (e.g., survivin, hIERI) 4 Mutated, unique TAAs The TAAs recognized by…
