Follow-Up Care
– Day 100 evaluation Additional evaluation Aplastic anemia Bone marrow biopsy/aspirate for path, flow, and FISH for MDS panel EBV titers monthly posttransplant × 12 months – Chimerismsa – – CBC…
Engraftment
Major criteria Minor criteria T ≥ 38.3 °C with no identifiable infectious etiology Hepatic dysfunction with either total bilirubin ≥ 2 mg/dL or transaminase levels ≥ 2x ULN Erythrodermatous rash involving > 25 % BSA and not…
Transfusion Medicine
Suspected TRALI Acute onset within 6 h of blood transfusion PaO2/FiO2 < 300 mmHg, or worsening of P to F ratio Bilateral infiltrative changes on chest radiograph No sign of hydrostatic pulmonary edema…
Antithrombotic Guidelines
Aspirin – Primary prevention Stop Secondary prevention Stop during conditioning, resume when platelets > 50,000 Coronary stent – Bare metal Combined therapy (ASA = aspirin + P2Y12 Inhibitor) 4 weeks, then ASA thereafter….
Graft-Versus-Host Disease Prophylaxis
Creatinine (mg/dL) Cyclosporine/tacrolimus dose 1.5–1.75 (or 1–1.5 × baseline) 50–75 % of current dose 1.76–2 (or 1.6–1.9 × baseline) 25–50 % of current dose > 2 (or > 1.9 × baseline) Hold until creatinine < 2 then resume…
Infection Prophylaxis
VZV−/HSV− VZV−/HSV+ VZV+/HSV−/+ Autologous No prophylaxis required Acyclovir 800 mg po daily through day + 365 Acyclovir 800 mg po daily through day + 365 Allogeneic No prophylaxis requireda Acyclovir 800 mg po BID…
Adolescent and Young Adult Concerns
Domain Examples Medical Oncology, palliation, nutrition, endocrinology, etc. Emotional Psychology, coping, distress Physical Exercise, activities of daily living, myopathy Neurocognitive Education, vocation Social Relationships with peers and providers Reproductive Fertility…
Physical and Occupational Therapy
6 How you feel when lying in bed or sitting in a chair, relaxed. Little or no effort 7 Very, very light 8 9 Very light 10 11 Fairly light …
Overview of Hematopoietic Stem Cell Transplantation
© Springer Science+Business Media, LLC 2015Richard T. Maziarz and Susan Schubach Slater (eds.)Blood and Marrow Transplant Handbook10.1007/978-3-319-13832-9_1 1. Overview of Hematopoietic Stem Cell Transplantation Richard T. Maziarz1 (1) Center for Hematologic Malignancies, Adult Blood and Marrow…
