Alcohol and Cancer: An Overview with Special Emphasis on the Role of Acetaldehyde and Cytochrome P450 2E1

Jan 31, 2017 by in ONCOLOGY Comments Off on Alcohol and Cancer: An Overview with Special Emphasis on the Role of Acetaldehyde and Cytochrome P450 2E1

Carcinogenesis 1. Acetaldehyde 2. Oxidative stress: induction of cytochrome P450 2E1 and reactive oxygen species 3. Retinoids 4. Epigenetic changes 5. Cancer genes and signaling pathways Mitogenic signals: MAPK, RAS Insensitivity to antigrowth signals: Rb…

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Introduction

Jan 31, 2017 by in ONCOLOGY Comments Off on Introduction

20. McClain CJ et al (1998) Tumor necrosis factor and alcoholic liver disease. Alcohol Clin Exp Res 22(5 Suppl):248S–252SPubMedCrossRef Related posts: Transgenic Mouse Models for Alcohol Metabolism, Toxicity, and Cancer…

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