The Life History of ApoB Lipoprotein Particles

May 31, 2017 by in ENDOCRINOLOGY Comments Off on The Life History of ApoB Lipoprotein Particles

FIGURE 1.1 The apoB48 lipoprotein particle family consists of chylomicrons and chylomicron remnants (CR). Chylomicrons are secreted by intestinal cells following a meal and transport the dietary lipids to target…

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The Primary ApoB Dyslipoproteinemias

May 31, 2017 by in ENDOCRINOLOGY Comments Off on The Primary ApoB Dyslipoproteinemias

FIGURE 3.1 3.1 HyperTG NormoapoB This can be due to (Figure 3.1): 1) Increased chylomicron particles   2) Increased chylomicron particles and increased VLDL particles   3) Increased chylomicron and…

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ApoB in Cardiovascular Risk Prediction

May 31, 2017 by in ENDOCRINOLOGY Comments Off on ApoB in Cardiovascular Risk Prediction

FIGURE 5.1 The measurement of LDL-C has major limitations, which have not received the attention the issue deserves. If LDL-C is calculated by the Friedewald formula, as it is in…

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Secondary ApoB Dyslipoproteinemias

May 31, 2017 by in ENDOCRINOLOGY Comments Off on Secondary ApoB Dyslipoproteinemias

FIGURE 4.1 4.2.1 HyperTG HyperapoB: Increased VLDL and LDL Lipoprotein Particles Pathophysiology of Increased VLDL and LDL Particle Number The most frequently observed atherogenic dyslipoproteinemia in overweight or obese patients…

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ApoB Lipoprotein Particles: the preferred Treatment Target in Primary and Secondary Prevention

May 31, 2017 by in ENDOCRINOLOGY Comments Off on ApoB Lipoprotein Particles: the preferred Treatment Target in Primary and Secondary Prevention

Guideline LDL-C mmol/l  Non-HDL-C  apoB   Concentration mmol/l mg/dl NHANES Population percentile Concentration mmol/l mg/dl NHANES population percentile Concentration g/l NHANES population percentile National Lipid Association 197        High risk  < 2,6 < 100…

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