Enfuvirtide

Aug 11, 2016 by in INFECTIOUS DISEASE Comments Off on Enfuvirtide

Chapter 23 Enfuvirtide J. Michael Kilby, MD Prior to the accelerated FDA approval in 2003 of the membrane fusion inhibitor, enfuvirtide (ENF), all available antiretroviral agents were directed against one…

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Microsporidiosis

Aug 11, 2016 by in INFECTIOUS DISEASE Comments Off on Microsporidiosis

Chapter 39 Microsporidiosis Louis M. Weiss, MD, MPH Microsporidia is a nontaxonomic designation used to refer to a group of obligate, intracellular parasites belonging to the phylum Microsporidia.1,2 The Microsporidia…

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Ritonavir

Aug 11, 2016 by in INFECTIOUS DISEASE Comments Off on Ritonavir

Chapter 16 Ritonavir Sven A. Danner, MD, PhD Ritonavir (RTV) is an inhibitor of the protease enzyme encoded by the human immunodeficiency virus (HIV) (Fig. 16-1). The chemical structure of…

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Hepatitis C Infection

Aug 11, 2016 by in INFECTIOUS DISEASE Comments Off on Hepatitis C Infection

Chapter 55 Hepatitis C Infection Mark S. Sulkowski, MD Human immunodeficiency virus (HIV)-infected persons have an increased incidence of hepatitis C and an accelerated course of chronic liver disease, leading…

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Didanosine

Aug 11, 2016 by in INFECTIOUS DISEASE Comments Off on Didanosine

Chapter 6 Didanosine Raphael Dolin, MD STRUCTURE Didanosine (2′,3′-dideoxyinosine, ddI, Videx, Videx EC) is a nucleoside analog active against human immunodeficiency virus type 1 (HIV-1), HIV-2, simian immunodeficiency virus, and…

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Adrenal, Gonadal, and Thyroid Disorders

Aug 11, 2016 by in INFECTIOUS DISEASE Comments Off on Adrenal, Gonadal, and Thyroid Disorders

Chapter 76 Adrenal, Gonadal, and Thyroid Disorders Joan C. Lo, MD, Morris Schambelan, MD A variety of endocrine disorders have been reported in association with human immunodeficiency virus (HIV) infection…

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